Sweet recipe for cellular closeness
Protein halts modification of glycoproteins, encouraging germ cells to stay tight.
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Research Highlights
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Migrating cells CLIC into gear
A clathrin-independent pathway is the predominant endocytic mechanism in fibroblasts, say Howes et al., and it boosts cell migration by rapidly internalizing adhesion proteins.
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Myosin II contracts out GTPase activation
Lee et al. report that contractile myosin filaments bind guanine nucleotide exchange factors (GEFs) to prevent the activation of Rho family GTPases, potentially coordinating the…
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The cytoplasm gets some new threads
Cytoskeletal proteins aren't the only filament-forming molecules in cells, say Noree et al., who identify several metabolic enzymes and translation factors that also assemble…
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Casting the autophagy net
Two studies investigate how cells regulate the formation of autophagosomes.
