Endogenous muscle lectin inhibits myoblast adhesion to laminin

doi:10.1083/jcb.115.5.1437

This Article

	Full Text (PDF, 1606K)
	Alert me when this article is cited
	Citation Map

Services

	Email this article
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new content in the JCB
	Download to citation manager

Citing Articles

	Citing Articles via HighWire
	Citing Articles via CrossRef
	Citing Articles via Google Scholar

Google Scholar

	Articles by Cooper, D. N.
	Articles by Barondes, S. H.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Cooper, D. N.
	Articles by Barondes, S. H.


Social Bookmarking

	What's this?

ARTICLES

Endogenous muscle lectin inhibits myoblast adhesion to laminin

DN Cooper, SM Massa and SH Barondes
Department of Psychiatry, University of California, San Francisco 94143.

L-14, a dimeric lactose-binding lectin with subunits of 14 kD, is expressed in a wide range of vertebrate tissues. Several functions have been postulated for this lectin, but definitive evidence for a specific biological role has been elusive. In muscle, L-14 is secreted during differentiation and accumulates with laminin in basement membrane surrounding each myofiber. Here we present evidence that laminin is a major glycoprotein ligand for L-14 in differentiating mouse C2C12 muscle cells and that binding of secreted L-14 to polylactosamine oligosaccharides of substrate laminin induces loss of cell-substratum adhesion. These results suggest that one function of L-14 is to regulate myoblast detachment from laminin during differentiation and fusion into tubular myofibers.
Add to CiteULike CiteULike Add to Complore Complore Add to Connotea Connotea Add to Del.icio.us Del.icio.us Add to Digg Digg Facebook Add to Reddit Reddit Add to Technorati Technorati Twitter What's this?

This article has been cited by other articles:

Poisa-Beiro, L., Dios, S., Ahmed, H., Vasta, G. R., Martinez-Lopez, A., Estepa, A., Alonso-Gutierrez, J., Figueras, A., Novoa, B. (2009). Nodavirus Infection of Sea Bass (Dicentrarchus labrax) Induces Up-Regulation of Galectin-1 Expression with Potential Anti-Inflammatory Activity. J. Immunol. 183: 6600-6611 [Abstract] [Full Text]
Saravanan, C., Liu, F.-T., Gipson, I. K., Panjwani, N. (2009). Galectin-3 promotes lamellipodia formation in epithelial cells by interacting with complex N-glycans on {alpha}3{beta}1 integrin. J. Cell Sci. 122: 3684-3693 [Abstract] [Full Text]
Cerri, D. G., Rodrigues, L. C., Stowell, S. R., Araujo, D. D., Coelho, M. C., Oliveira, S. R., Bizario, J. C. S., Cummings, R. D., Dias-Baruffi, M., Costa, M. C. R. (2008). Degeneration of dystrophic or injured skeletal muscles induces high expression of Galectin-1. Glycobiology 18: 842-850 [Abstract] [Full Text]
Stowell, S. R., Arthur, C. M., Mehta, P., Slanina, K. A., Blixt, O., Leffler, H., Smith, D. F., Cummings, R. D. (2008). Galectin-1, -2, and -3 Exhibit Differential Recognition of Sialylated Glycans and Blood Group Antigens. J. Biol. Chem. 283: 10109-10123 [Abstract] [Full Text]
Camby, I., Le Mercier, M., Lefranc, F., Kiss, R. (2006). Galectin-1: a small protein with major functions. Glycobiology 16: 137R-157R [Abstract] [Full Text]
Perone, M. J., Bertera, S., Tawadrous, Z. S., Shufesky, W. J., Piganelli, J. D., Baum, L. G., Trucco, M., Morelli, A. E. (2006). Dendritic Cells Expressing Transgenic Galectin-1 Delay Onset of Autoimmune Diabetes in Mice. J. Immunol. 177: 5278-5289 [Abstract] [Full Text]
Patnaik, S. K., Potvin, B., Carlsson, S., Sturm, D., Leffler, H., Stanley, P. (2006). Complex N-glycans are the major ligands for galectin-1, -3, and -8 on Chinese hamster ovary cells. Glycobiology 16: 305-317 [Abstract] [Full Text]
Venkataraman, N., Cole, A. L., Svoboda, P., Pohl, J., Cole, A. M. (2005). Cationic Polypeptides Are Required for Anti-HIV-1 Activity of Human Vaginal Fluid. J. Immunol. 175: 7560-7567 [Abstract] [Full Text]
Nio, J., Kon, Y., Iwanaga, T. (2005). Differential Cellular Expression of Galectin Family mRNAs in the Epithelial Cells of the Mouse Digestive Tract. J. Histochem. Cytochem. 53: 1323-1334 [Abstract] [Full Text]
Stowell, S. R., Dias-Baruffi, M., Penttila, L., Renkonen, O., Nyame, A. K., Cummings, R. D. (2004). Human galectin-1 recognition of poly-N-acetyllactosamine and chimeric polysaccharides. Glycobiology 14: 157-167 [Abstract] [Full Text]
Martin, P. T. (2003). Dystroglycan glycosylation and its role in matrix binding in skeletal muscle. Glycobiology 13: 55R-66R [Abstract] [Full Text]
Maeda, N., Kawada, N., Seki, S., Arakawa, T., Ikeda, K., Iwao, H., Okuyama, H., Hirabayashi, J., Kasai, K.-i., Yoshizato, K. (2003). Stimulation of Proliferation of Rat Hepatic Stellate Cells by Galectin-1 and Galectin-3 through Different Intracellular Signaling Pathways. J. Biol. Chem. 278: 18938-18944 [Abstract] [Full Text]
Cao, Z., Said, N., Amin, S., Wu, H. K., Bruce, A., Garate, M., Hsu, D. K., Kuwabara, I., Liu, F.-T., Panjwani, N. (2002). Galectins-3 and -7, but not Galectin-1, Play a Role in Re-epithelialization of Wounds. J. Biol. Chem. 277: 42299-42305 [Abstract] [Full Text]
Ahmed, H., Bianchet, M. A., Amzel, L. M., Hirabayashi, J., Kasai, K.-i., Giga-Hama, Y., Tohda, H., Vasta, G. R. (2002). Novel carbohydrate specificity of the 16-kDa galectin from Caenorhabditis elegans: binding to blood group precursor oligosaccharides (type 1, type 2, T{alpha}, and T{beta}) and gangliosides. Glycobiology 12: 451-461 [Abstract] [Full Text]
Almkvist, J., Dahlgren, C., Leffler, H., Karlsson, A. (2002). Activation of the Neutrophil Nicotinamide Adenine Dinucleotide Phosphate Oxidase by Galectin-1. J. Immunol. 168: 4034-4041 [Abstract] [Full Text]
Pace, K. E., Lebestky, T., Hummel, T., Arnoux, P., Kwan, K., Baum, L. G. (2002). Characterization of a Novel Drosophila melanogaster Galectin. EXPRESSION IN DEVELOPING IMMUNE, NEURAL, AND MUSCLE TISSUES. J. Biol. Chem. 277: 13091-13098 [Abstract] [Full Text]
Kuwabara, I., Kuwabara, Y., Yang, R.-Y., Schuler, M., Green, D. R., Zuraw, B. L., Hsu, D. K., Liu, F.-T. (2002). Galectin-7 (PIG1) Exhibits Pro-apoptotic Function through JNK Activation and Mitochondrial Cytochrome c Release. J. Biol. Chem. 277: 3487-3497 [Abstract] [Full Text]
Goldring, K., Jones, G. E., Thiagarajah, R., Watt, D. J. (2002). The effect of galectin-1 on the differentiation of fibroblasts and myoblasts in vitro. J. Cell Sci. 115: 355-366 [Abstract] [Full Text]
Timmons, P. M., Rigby, P. W. J., Poirier, F. (2002). The murine seminiferous epithelial cycle is pre-figured in the Sertoli cells of the embryonic testis. Development 129: 635-647 [Abstract] [Full Text]
Lee, Y.-N., Kang, J.-S., Krauss, R. S. (2001). Identification of a Role for the Sialomucin CD164 in Myogenic Differentiation by Signal Sequence Trapping in Yeast. Mol. Cell. Biol. 21: 7696-7706 [Abstract] [Full Text]
Park, J. W., Voss, P. G., Grabski, S., Wang, J. L., Patterson, R. J. (2001). Association of galectin-1 and galectin-3 with Gemin4 in complexes containing the SMN protein. Nucleic Acids Res 29: 3595-3602 [Abstract] [Full Text]
Boulianne, R. P., Liu, Y., Aebi, M., Lu, B. C., Kües, U. (2000). Fruiting body development in Coprinus cinereus: regulated expression of two galectins secreted by a non-classical pathway. Microbiology 146: 1841-1853 [Abstract] [Full Text]
Hadari, Y., Arbel-Goren, R, Levy, Y, Amsterdam, A, Alon, R, Zakut, R, Zick, Y (2000). Galectin-8 binding to integrins inhibits cell adhesion and induces apoptosis. J. Cell Sci. 113: 2385-2397 [Abstract]
Bernerd, F., Sarasin, A., Magnaldo, T. (1999). Galectin-7 overexpression is associated with the apoptotic process in UVB-induced sunburn keratinocytes. Proc. Natl. Acad. Sci. USA 96: 11329-11334 [Abstract] [Full Text]
Choi, J., van Wijnen, A., Aslam, F, Leszyk, J., Stein, J., Stein, G., Lian, J., Penman, S (1998). Developmental association of the beta-galactoside-binding protein galectin-1 with the nuclear matrix of rat calvarial osteoblasts. J. Cell Sci. 111: 3035-3043 [Abstract]
Wada, J., Kanwar, Y. S. (1997). Identification and Characterization of Galectin-9, a Novel beta -Galactoside-binding Mammalian Lectin. J. Biol. Chem. 272: 6078-6086 [Abstract] [Full Text]
Wasano, K., Hirakawa, Y. (1997). Recombinant Galectin-1 Recognizes Mucin and Epithelial Cell Surface Glycocalyces of Gastrointestinal Tract. J. Histochem. Cytochem. 45: 275-284 [Abstract] [Full Text]
Cooper, D. N.W., Boulianne, R. P., Charlton, S., Farrell, E. M., Sucher, A., Lu, B. C. (1997). Fungal Galectins, Sequence and Specificity of Two Isolectins from Coprinus cinereus. J. Biol. Chem. 272: 1514-1521 [Abstract] [Full Text]
Hirabayashi, J., Ubukata, T., Kasai, K.-i. (1996). Purification and Molecular Characterization of a Novel 16-kDa Galectin from the Nematode Caenorhabditis elegans. J. Biol. Chem. 271: 2497-2505 [Abstract] [Full Text]
Martin, P., Ettinger, A., Sanes, JR (1995). A synaptic localization domain in the synaptic cleft protein laminin beta 2 (s-laminin). Science 269: 413-416 [Abstract]
Madsen, P., Rasmussen, H. H., Flint, T., Gromov, P., Kruse, T. A., Honor�, B., Vorum, H., Celis, J. E. (1995). Cloning, Expression, and Chromosome Mapping of Human Galectin-7. J. Biol. Chem. 270: 5823-5829 [Abstract] [Full Text]
Gitt, M. A., Wiser, M. F., Leffler, H., Herrmann, J., Xia, Y.-R., Massa, S. M., Cooper, D. N. W., Lusis, A. J., Barondes, S. H. (1995). Sequence and Mapping of Galectin-5, a beta-Galactoside-binding Lectin, Found in Rat Erythrocytes. J. Biol. Chem. 270: 5032-5038 [Abstract] [Full Text]
Cho, M., Cummings, R. D. (1995). Galectin-1, a beta-Galactoside-binding Lectin in Chinese Hamster Ovary Cells. J. Biol. Chem. 270: 5198-5206 [Abstract] [Full Text]
Cho, M., Cummings, R. D. (1995). Galectin-1, a beta-Galactoside-binding Lectin in Chinese Hamster Ovary Cells. J. Biol. Chem. 270: 5207-5212 [Abstract] [Full Text]
Hadari, Y. R., Paz, K., Dekel, R., Mestrovic, T., Accili, D., Zick, Y. (1995). Galectin-8. J. Biol. Chem. 270: 3447-3453 [Abstract] [Full Text]
Bao, Q, Hughes, R. (1995). Galectin-3 expression and effects on cyst enlargement and tubulogenesis in kidney epithelial MDCK cells cultured in three-dimensional matrices in vitro. J. Cell Sci. 108: 2791-2800 [Abstract]
Mahanthappa, N., Cooper, D., Barondes, S., Schwarting, G. (1994). Rat olfactory neurons can utilize the endogenous lectin, L-14, in a novel adhesion mechanism. Development 120: 1373-1384 [Abstract]
Gu, M, Wang, W, Song, W., Cooper, D., Kaufman, S. (1994). Selective modulation of the interaction of alpha 7 beta 1 integrin with fibronectin and laminin by L-14 lectin during skeletal muscle differentiation. J. Cell Sci. 107: 175-181 [Abstract]
Levy, Y., Arbel-Goren, R., Hadari, Y. R., Eshhar, S., Ronen, D., Elhanany, E., Geiger, B., Zick, Y. (2001). Galectin-8 Functions as a Matricellular Modulator of Cell Adhesion. J. Biol. Chem. 276: 31285-31295 [Abstract] [Full Text]