SED5 encodes a 39-kD integral membrane protein required for vesicular transport between the ER and the Golgi complex

doi:10.1083/jcb.119.3.513

This Article

Full Text (PDF, 2881K)

Alert me when this article is cited

Citation Map

Services

Email this article

Similar articles in this journal

Similar articles in PubMed

Alert me to new content in the JCB

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via CrossRef

Citing Articles via Google Scholar

Google Scholar

Articles by Hardwick, K. G.

Articles by Pelham, H. R.

Search for Related Content

PubMed

PubMed Citation

Articles by Hardwick, K. G.

Articles by Pelham, H. R.

Pubmed/NCBI databases

Gene	Genome
GEO Profiles	HomoloGene
Protein
Substance via MeSH

Social Bookmarking

What's this?

ARTICLES

SED5 encodes a 39-kD integral membrane protein required for vesicular transport between the ER and the Golgi complex

KG Hardwick and HR Pelham
MRC Laboratory of Molecular Biology, Cambridge, United Kingdom.

The ERD2 gene, which encodes the yeast HDEL (His-Asp-Glu-Leu) receptor, is essential for growth (Semenza, J. C., K. G. Hardwick, N. Dean, and H. R. B. Pelham. 1990. Cell. 61:1349-1357; Lewis, M. J., D. J. Sweet, and H. R. B. Pelham. 1990. Cell. 61:1359-1363). SED5, when present in multiple copies, enables cells to grow in the absence of Erd2p. Sequence analysis of SED5 reveals no significant homology with ERD2 or other known genes. We have raised antibodies to Sed5p which specifically recognize a 39-kD integral membrane protein. A stretch of hydrophobic residues at the COOH terminus is predicted to hold Sed5p on the cytoplasmic face of intracellular membranes. Cells that are depleted of Sed5p are unable to transport carboxypeptidase Y to the Golgi complex, and stop growing after a dramatic accumulation of ER membranes and vesicles. We conclude that the SED5 gene is essential for growth and that Sed5p is required for ER to Golgi transport. When Sed5p is overexpressed the efficiency of ER to Golgi transport is reduced, vesicles accumulate, and cellular morphology is perturbed. Immunofluorescence studies reveal that the bulk of Sed5p is not found on ER membranes but on punctate structures throughout the cytoplasm, the number of which increases upon SED5 overexpression. We suggest that Sed5p has an essential role in vesicular transport between ER and Golgi compartments and that it may itself cycle between these organelles.
Add to CiteULike CiteULike Add to Complore Complore Add to Connotea Connotea Add to Del.icio.us Del.icio.us Add to Digg Digg Facebook Add to Reddit Reddit Add to Technorati Technorati Twitter What's this?

This article has been cited by other articles:

Sudhof, T. C., Rothman, J. E. (2009). Membrane Fusion: Grappling with SNARE and SM Proteins. Science 323: 474-477 [Abstract] [Full Text]
Elias, E. V., Quiroga, R., Gottig, N., Nakanishi, H., Nash, T. E., Neiman, A., Lujan, H. D. (2008). Characterization of SNAREs Determines the Absence of a Typical Golgi Apparatus in the Ancient Eukaryote Giardia lamblia. J. Biol. Chem. 283: 35996-36010 [Abstract] [Full Text]
Bao, Y., Lopez, J. A., James, D. E., Hunziker, W. (2008). Snapin Interacts with the Exo70 Subunit of the Exocyst and Modulates GLUT4 Trafficking. J. Biol. Chem. 283: 324-331 [Abstract] [Full Text]
Kama, R., Robinson, M., Gerst, J. E. (2007). Btn2, a Hook1 Ortholog and Potential Batten Disease-Related Protein, Mediates Late Endosome-Golgi Protein Sorting in Yeast. Mol. Cell. Biol. 27: 605-621 [Abstract] [Full Text]
Welsh, L. M., Tong, A. H. Y., Boone, C., Jensen, O. N., Otte, S. (2006). Genetic and molecular interactions of the Erv41p-Erv46p complex involved in transport between the endoplasmic reticulum and Golgi complex. J. Cell Sci. 119: 4730-4740 [Abstract] [Full Text]
Reggiori, F., Klionsky, D. J. (2006). Atg9 sorting from mitochondria is impaired in early secretion and VFT-complex mutants in Saccharomyces cerevisiae. J. Cell Sci. 119: 2903-2911 [Abstract] [Full Text]
Robinson, M., Poon, P. P., Schindler, C., Murray, L. E., Kama, R., Gabriely, G., Singer, R. A., Spang, A., Johnston, G. C., Gerst, J. E. (2006). The Gcs1 Arf-GAP Mediates Snc1,2 v-SNARE Retrieval to the Golgi in Yeast. Mol. Biol. Cell 17: 1845-1858 [Abstract] [Full Text]
Flanagan, J. J., Barlowe, C. (2006). Cysteine-Disulfide Cross-linking to Monitor SNARE Complex Assembly during Endoplasmic Reticulum-Golgi Transport. J. Biol. Chem. 281: 2281-2288 [Abstract] [Full Text]
Chatre, L., Brandizzi, F., Hocquellet, A., Hawes, C., Moreau, P. (2005). Sec22 and Memb11 Are v-SNAREs of the Anterograde Endoplasmic Reticulum-Golgi Pathway in Tobacco Leaf Epidermal Cells. Plant Physiol. 139: 1244-1254 [Abstract] [Full Text]
Castillo-Flores, A., Weinberger, A., Robinson, M., Gerst, J. E. (2005). Mso1 Is a Novel Component of the Yeast Exocytic SNARE Complex. J. Biol. Chem. 280: 34033-34041 [Abstract] [Full Text]
Weinberger, A., Kamena, F., Kama, R., Spang, A., Gerst, J. E. (2005). Control of Golgi Morphology and Function by Sed5 t-SNARE Phosphorylation. Mol. Biol. Cell 16: 4918-4930 [Abstract] [Full Text]
Inadome, H., Noda, Y., Adachi, H., Yoda, K. (2005). Immunoisolaton of the Yeast Golgi Subcompartments and Characterization of a Novel Membrane Protein, Svp26, Discovered in the Sed5-Containing Compartments. Mol. Cell. Biol. 25: 7696-7710 [Abstract] [Full Text]
Koffel, R., Tiwari, R., Falquet, L., Schneiter, R. (2005). The Saccharomyces cerevisiae YLL012/YEH1, YLR020/YEH2, and TGL1 Genes Encode a Novel Family of Membrane-Anchored Lipases That Are Required for Steryl Ester Hydrolysis. Mol. Cell. Biol. 25: 1655-1668 [Abstract] [Full Text]
Bruinsma, P., Spelbrink, R. G., Nothwehr, S. F. (2004). Retrograde Transport of the Mannosyltransferase Och1p to the Early Golgi Requires a Component of the COG Transport Complex. J. Biol. Chem. 279: 39814-39823 [Abstract] [Full Text]
Volchuk, A., Ravazzola, M., Perrelet, A., Eng, W. S., Di Liberto, M., Varlamov, O., Fukasawa, M., Engel, T., Sollner, T. H., Rothman, J. E., Orci, L. (2004). Countercurrent Distribution of Two Distinct SNARE Complexes Mediating Transport within the Golgi Stack. Mol. Biol. Cell 15: 1506-1518 [Abstract] [Full Text]
Varlamov, O., Volchuk, A., Rahimian, V., Doege, C. A., Paumet, F., Eng, W. S., Arango, N., Parlati, F., Ravazzola, M., Orci, L., Sollner, T. H., Rothman, J. E. (2004). i-SNAREs: inhibitory SNAREs that fine-tune the specificity of membrane fusion. JCB 164: 79-88 [Abstract] [Full Text]
Masaki, R., Kameyama, K., Yamamoto, A. (2003). Post-Translational Targeting of a Tail-Anchored Green Fluorescent Protein to the Endolpasmic Reticulum. J Biochem 134: 415-426 [Abstract] [Full Text]
Tatzer, V., Zellnig, G., Kohlwein, S. D., Schneiter, R. (2002). Lipid-dependent Subcellular Relocalization of the Acyl Chain Desaturase in Yeast. Mol. Biol. Cell 13: 4429-4442 [Abstract] [Full Text]
Rancour, D. M., Dickey, C. E., Park, S., Bednarek, S. Y. (2002). Characterization of AtCDC48. Evidence for Multiple Membrane Fusion Mechanisms at the Plane of Cell Division in Plants. Plant Physiol. 130: 1241-1253 [Abstract] [Full Text]
Friedmann, E., Salzberg, Y., Weinberger, A., Shaltiel, S., Gerst, J. E. (2002). YOS9, the Putative Yeast Homolog of a Gene Amplified in Osteosarcomas, Is Involved in the Endoplasmic Reticulum (ER)-Golgi Transport of GPI-anchored Proteins. J. Biol. Chem. 277: 35274-35281 [Abstract] [Full Text]
Liu, Y., Barlowe, C. (2002). Analysis of Sec22p in Endoplasmic Reticulum/Golgi Transport Reveals Cellular Redundancy in SNARE Protein Function. Mol. Biol. Cell 13: 3314-3324 [Abstract] [Full Text]
Taxis, C., Vogel, F., Wolf, D. H. (2002). ER-Golgi Traffic Is a Prerequisite for Efficient ER Degradation. Mol. Biol. Cell 13: 1806-1818 [Abstract] [Full Text]
Peng, R., Gallwitz, D. (2002). Sly1 protein bound to Golgi syntaxin Sed5p allows assembly and contributes to specificity of SNARE fusion complexes. JCB 157: 645-655 [Abstract] [Full Text]
Parlati, F., Varlamov, O., Paz, K., McNew, J. A., Hurtado, D., Sollner, T. H., Rothman, J. E. (2002). Distinct SNARE complexes mediating membrane fusion in Golgi transport based on combinatorial specificity. Proc. Natl. Acad. Sci. USA 99: 5424-5429 [Abstract] [Full Text]
Jantti, J., Aalto, M. K., Oyen, M., Sundqvist, L., Keranen, S., Ronne, H. (2002). Characterization of temperature-sensitive mutations in the yeast syntaxin 1 homologues Sso1p and Sso2p, and evidence of a distinct function for Sso1p in sporulation. J. Cell Sci. 115: 409-420 [Abstract] [Full Text]
Reilly, B. A., Kraynack, B. A., VanRheenen, S. M., Waters, M. G. (2001). Golgi-to-Endoplasmic Reticulum (ER) Retrograde Traffic in Yeast Requires Dsl1p, a Component of the ER Target Site that Interacts with a COPI Coat Subunit. Mol. Biol. Cell 12: 3783-3796 [Abstract] [Full Text]
Kasai, K., Akagawa, K. (2001). Roles of the cytoplasmic and transmembrane domains of syntaxins in intracellular localization and trafficking. J. Cell Sci. 114: 3115-3124 [Abstract] [Full Text]
Bensen, E. S., Yeung, B. G., Payne, G. S. (2001). Ric1p and the Ypt6p GTPase Function in a Common Pathway Required for Localization of Trans-Golgi Network Membrane Proteins. Mol. Biol. Cell 12: 13-26 [Abstract] [Full Text]
Sanderfoot, A. A., Assaad, F. F., Raikhel, N. V. (2000). The Arabidopsis Genome. An Abundance of Soluble N-Ethylmaleimide-Sensitive Factor Adaptor Protein Receptors. Plant Physiol. 124: 1558-1569 [Abstract] [Full Text]
Gurunathan, S., Chapman-Shimshoni, D., Trajkovic, S., Gerst, J. E. (2000). Yeast Exocytic v-SNAREs Confer Endocytosis. Mol. Biol. Cell 11: 3629-3643 [Abstract] [Full Text]
Neiman, A. M., Katz, L., Brennwald, P. J. (2000). Identification of Domains Required for Developmentally Regulated SNARE Function in Saccharomyces cerevisiae. Genetics 155: 1643-1655 [Abstract] [Full Text]
Steegmaier, M., Oorschot, V., Klumperman, J., Scheller, R. H. (2000). Syntaxin 17 Is Abundant in Steroidogenic Cells and Implicated in Smooth Endoplasmic Reticulum Membrane Dynamics. Mol. Biol. Cell 11: 2719-2731 [Abstract] [Full Text]
Allan, B. B., Moyer, B. D., Balch, W. E. (2000). Rab1 Recruitment of p115 into a cis-SNARE Complex: Programming Budding COPII Vesicles for Fusion. Science 289: 444-448 [Abstract] [Full Text]
Bassham, D. C., Sanderfoot, A. A., Kovaleva, V., Zheng, H., Raikhel, N. V. (2000). AtVPS45 Complex Formation at the trans-Golgi Network. Mol. Biol. Cell 11: 2251-2265 [Abstract] [Full Text]
Cao, X., Barlowe, C. (2000). Asymmetric Requirements for a Rab Gtpase and Snare Proteins in Fusion of Copii Vesicles with Acceptor Membranes. JCB 149: 55-66 [Abstract] [Full Text]
VanRheenen, S. M., Cao, X., Sapperstein, S. K., Chiang, E. C., Lupashin, V. V., Barlowe, C., Waters, M. G. (1999). Sec34p, a Protein Required for Vesicle Tethering to the Yeast Golgi Apparatus, Is in a Complex with Sec35p. JCB 147: 729-742 [Abstract] [Full Text]
Sanderfoot, A. A., Kovaleva, V., Zheng, H., Raikhel, N. V. (1999). The t-SNARE AtVAM3p Resides on the Prevacuolar Compartment in Arabidopsis Root Cells. Plant Physiol. 121: 929-938 [Abstract] [Full Text]
Bock, J. B., Scheller, R. H. (1999). SNARE proteins mediate lipid bilayer fusion. Proc. Natl. Acad. Sci. USA 96: 12227-12229 [Full Text]
Advani, R. J., Yang, B., Prekeris, R., Lee, K. C., Klumperman, J., Scheller, R. H. (1999). Vamp-7 Mediates Vesicular Transport from Endosomes to Lysosomes. JCB 146: 765-776 [Abstract] [Full Text]
Wittke, S., Lewke, N., Müller, S., Johnsson, N. (1999). Probing the Molecular Environment of Membrane Proteins In Vivo. Mol. Biol. Cell 10: 2519-2530 [Abstract] [Full Text]
von Mollard, G. F., Stevens, T. H. (1999). The Saccharomyces cerevisiae v-SNARE Vti1p Is Required for Multiple Membrane Transport Pathways to the Vacuole. Mol. Biol. Cell 10: 1719-1732 [Abstract] [Full Text]
Peng, R., Grabowski, R., De Antoni, A., Gallwitz, D. (1999). Specific interaction of the yeast cis-Golgi syntaxin Sed5p and the coat protein complex II component Sec24p of endoplasmic reticulum-derived transport vesicles. Proc. Natl. Acad. Sci. USA 96: 3751-3756 [Abstract] [Full Text]
Zhang, T., Wong, S. H., Tang, B. L., Xu, Y., Hong, W. (1999). Morphological and Functional Association of Sec22b/ERS-24 with the pre-Golgi Intermediate Compartment. Mol. Biol. Cell 10: 435-453 [Abstract] [Full Text]
Ossipov, D, Schroder-Kohne, S, Schmitt, H. (1999). Yeast ER-Golgi v-SNAREs Bos1p and Bet1p differ in steady-state localization and targeting. J. Cell Sci. 112: 4135-4142 [Abstract]
Wong, S. H., Xu, Y., Zhang, T., Griffiths, G., Lowe, S. L., Subramaniam, V. N., Seow, K. T., Hong, W. (1999). GS32, a Novel Golgi SNARE of 32�kDa, Interacts Preferentially with Syntaxin 6. Mol. Biol. Cell 10: 119-134 [Abstract] [Full Text]
Holthuis, J. C.�M., Nichols, B. J., Pelham, H. R.�B. (1998). The Syntaxin Tlg1p Mediates Trafficking of Chitin Synthase III to Polarized Growth Sites in Yeast. Mol. Biol. Cell 9: 3383-3397 [Abstract] [Full Text]
David, D., Sundarababu, S., Gerst, J. E. (1998). Involvement of Long Chain Fatty Acid Elongation in the Trafficking of Secretory Vesicles in Yeast. JCB 143: 1167-1182 [Abstract] [Full Text]
Rayner, J. C., Munro, S. (1998). Identification of the MNN2 and MNN5 Mannosyltransferases Required for Forming and Extending the Mannose Branches of the Outer Chain Mannans of Saccharomyces cerevisiae. J. Biol. Chem. 273: 26836-26843 [Abstract] [Full Text]
Wooding, S., Pelham, H. R.B. (1998). The Dynamics of Golgi Protein Traffic Visualized in Living Yeast Cells. Mol. Biol. Cell 9: 2667-2680 [Abstract] [Full Text]
Xu, Y., Wong, S. H., Tang, B. L., Subramaniam, V. N., Zhang, T., Hong, W. (1998). A 29-Kilodalton Golgi Soluble N-Ethylmaleimide-sensitive Factor Attachment Protein Receptor (Vti1-rp2) Implicated in Protein Trafficking in the Secretory Pathway. J. Biol. Chem. 273: 21783-21789 [Abstract] [Full Text]
Isenmann, S., Khew-Goodall, Y., Gamble, J., Vadas, M., Wattenberg, B. W. (1998). A Splice-Isoform of Vesicle-associated Membrane Protein-1 (VAMP-1) Contains a Mitochondrial Targeting Signal. Mol. Biol. Cell 9: 1649-1660 [Abstract] [Full Text]
Hay, J. C., Klumperman, J., Oorschot, V., Steegmaier, M., Kuo, C. S., Scheller, R. H. (1998). Localization, Dynamics, and Protein Interactions Reveal Distinct Roles for ER and Golgi SNAREs. JCB 141: 1489-1502 [Abstract] [Full Text]
VanRheenen, S. M., Cao, X., Lupashin, V. V., Barlowe, C., Gerard Waters, M. (1998). Sec35p, a Novel Peripheral Membrane Protein, Is Required for ER to Golgi Vesicle Docking. JCB 141: 1107-1119 [Abstract] [Full Text]
Jiang, Y., Al Scarpa, , Zhang, L., Stone, S., Feliciano, E., Ferro-Novick, S. (1998). A High Copy Suppressor Screen Reveals Genetic Interactions Between BET3 and a New Gene: Evidence for a Novel Complex in ER-to-Golgi Transport. Genetics 149: 833-841 [Abstract] [Full Text]
Abeliovich, H., Grote, E., Novick, P., Ferro-Novick, S. (1998). Tlg2p, a Yeast Syntaxin Homolog That Resides on the Golgi and Endocytic Structures. J. Biol. Chem. 273: 11719-11727 [Abstract] [Full Text]
Bryant, N. J., Stevens, T. H. (1998). Vacuole Biogenesis in Saccharomyces cerevisiae: Protein Transport Pathways to the Yeast Vacuole. Microbiol. Mol. Biol. Rev. 62: 230-247 [Abstract] [Full Text]
von Mollard, G. F., Stevens, T. H. (1998). A Human Homolog Can Functionally Replace the Yeast Vesicle-associated SNARE Vti1p in Two Vesicle Transport Pathways. J. Biol. Chem. 273: 2624-2630 [Abstract] [Full Text]
Rowe, T., Dascher, C., Bannykh, S., Plutner, H., Balch, W. E. (1998). Role of Vesicle-Associated Syntaxin 5 in the Assembly of Pre-Golgi Intermediates. Science 279: 696-700 [Abstract] [Full Text]
Hong, W (1998). Protein transport from the endoplasmic reticulum to the Golgi apparatus. J. Cell Sci. 111: 2831-2839 [Abstract]
Ballensiefen, W, Ossipov, D, Schmitt, H. (1998). Recycling of the yeast v-SNARE Sec22p involves COPI-proteins and the ER transmembrane proteins Ufe1p and Sec20p. J. Cell Sci. 111: 1507-1520 [Abstract]
Lee, F.-J. S., Huang, C.-F., Yu, W.-L., Buu, L.-M., Lin, C.-Y., Huang, M.-C., Moss, J., Vaughan, M. (1997). Characterization of an ADP-ribosylation Factor-like 1�Protein in Saccharomyces cerevisiae. J. Biol. Chem. 272: 30998-31005 [Abstract] [Full Text]
Barlowe, C. (1997). Coupled ER to Golgi Transport Reconstituted with Purified Cytosolic Proteins. JCB 139: 1097-1108 [Abstract] [Full Text]
Zhang, T., Wong, S. H., Tang, B. L., Xu, Y., Peter, F., Subramaniam, V. N., Hong, W. (1997). The Mammalian Protein (rbet1) Homologous to Yeast Bet1p Is Primarily Associated with the Pre-Golgi Intermediate Compartment and Is Involved in Vesicular Transport from the Endoplasmic Reticulum to the Golgi Apparatus. JCB 139: 1157-1168 [Abstract] [Full Text]
Lupashin, V. V., Pokrovskaya, I. D., McNew, J. A., Waters, M. G. (1997). Characterization of a Novel Yeast SNARE Protein Implicated in Golgi Retrograde Traffic. Mol. Biol. Cell 8: 2659-2676 [Abstract] [Full Text]
Subramaniam, V. N., Loh, E., Hong, W. (1997). N-Ethylmaleimide-sensitive Factor (NSF) and alpha -Soluble NSF Attachment Proteins (SNAP) Mediate Dissociation of GS28-Syntaxin 5�Golgi SNAP Receptors (SNARE) Complex. J. Biol. Chem. 272: 25441-25444 [Abstract] [Full Text]
Sato, M. H., Nakamura, N., Ohsumi, Y., Kouchi, H., Kondo, M., Hara-Nishimura, I., Nishimura, M., Wada, Y. (1997). The AtVAM3 Encodes a Syntaxin-related Molecule Implicated in the Vacuolar Assembly in Arabidopsis thaliana. J. Biol. Chem. 272: 24530-24535 [Abstract] [Full Text]
Burgess, R. W., Deitcher, D. L., Schwarz, T. L. (1997). The Synaptic Protein Syntaxin1 Is Required for Cellularization of Drosophila Embryos. JCB 138: 861-875 [Abstract] [Full Text]
Darsow, T., Rieder, S. E., Emr, S. D. (1997). A Multispecificity Syntaxin Homologue, Vam3p, Essential for Autophagic and Biosynthetic Protein Transport to the Vacuole. JCB 138: 517-529 [Abstract] [Full Text]
McNew, J. A., Sogaard, M., Lampen, N. M., Machida, S., Ye, R. R., Lacomis, L., Tempst, P., Rothman, J. E., Sollner, T. H. (1997). Ykt6p, a Prenylated SNARE Essential for Endoplasmic Reticulum-Golgi Transport. J. Biol. Chem. 272: 17776-17783 [Abstract] [Full Text]
Sacher, M., Stone, S., Ferro-Novick, S. (1997). The Synaptobrevin-related Domains of Bos1p and Sec22p Bind to the Syntaxin-like Region of Sed5p. J. Biol. Chem. 272: 17134-17138 [Abstract] [Full Text]
Mollard, G. F. v., Nothwehr, S. F., Stevens, T. H. (1997). The Yeast v-SNARE Vti1p Mediates Two Vesicle Transport Pathways through Interactions with the t-SNAREs Sed5p and Pep12p. JCB 137: 1511-1524 [Abstract] [Full Text]
Lupashin, V. V., Waters, M. G. (1997). t-SNARE Activation Through Transient Interaction with a Rab-Like Guanosine Triphosphatase. Science 276: 1255-1258 [Abstract] [Full Text]
Wada, Y, Nakamura, N, Ohsumi, Y, Hirata, A (1997). Vam3p, a new member of syntaxin related protein, is required for vacuolar assembly in the yeast Saccharomyces cerevisiae. J. Cell Sci. 110: 1299-1306 [Abstract]
Masaki, R., Yamamoto, A., Tashiro, Y. (1996). Membrane Topology and Retention of Microsomal Aldehyde Dehydrogenase in the Endoplasmic Reticulum. J. Biol. Chem. 271: 16939-16944 [Abstract] [Full Text]
Dascher, C., Balch, W. E. (1996). Mammalian Sly1 Regulates Syntaxin 5Function in Endoplasmic Reticulum to Golgi Transport. J. Biol. Chem. 271: 15866-15869 [Abstract] [Full Text]
Hay, J. C., Hirling, H., Scheller, R. H. (1996). Mammalian Vesicle Trafficking Proteins of the Endoplasmic Reticulum and Golgi Apparatus. J. Biol. Chem. 271: 5671-5679 [Abstract] [Full Text]
Tagaya, M., Toyonaga, S., Takahashi, M., Yamamoto, A., Fujiwara, T., Akagawa, K., Moriyama, Y., Mizushima, S. (1995). Syntaxin 1 (HPC-1) Is Associated with Chromaffin Granules. J. Biol. Chem. 270: 15930-15933 [Abstract] [Full Text]
Tellam, J. T., McIntosh, S., James, D. E. (1995). Molecular Identification of Two Novel Munc-18 Isoforms Expressed in Non-neuronal Tissues. J. Biol. Chem. 270: 5857-5863 [Abstract] [Full Text]
Pelham, H.R.B., Banfield, D.K., Lewis, M.J. (1995). SNAREs Involved in Traffic through the Golgi Complex. Cold Spring Harb Symp Quant Biol 60: 105-111 [Abstract]
Calakos, N, Bennett, M., Peterson, K., Scheller, R. (1994). Protein-protein interactions contributing to the specificity of intracellular vesicular trafficking. Science 263: 1146-1149 [Abstract]
Jantti, J, Keranen, S, Toikkanen, J, Kuismanen, E, Ehnholm, C, Soderlund, H, Olkkonen, V. (1994). Membrane insertion and intracellular transport of yeast syntaxin Sso2p in mammalian cells. J. Cell Sci. 107: 3623-3633 [Abstract]
Legesse-Miller, A., Sagiv, Y., Glozman, R., Elazar, Z. (2000). Aut7p, a Soluble Autophagic Factor, Participates in Multiple Membrane Trafficking Processes. J. Biol. Chem. 275: 32966-32973 [Abstract] [Full Text]
Misumi, Y., Sohda, M., Tashiro, A., Sato, H., Ikehara, Y. (2001). An Essential Cytoplasmic Domain for the Golgi Localization of Coiled-coil Proteins with a COOH-terminal Membrane Anchor. J. Biol. Chem. 276: 6867-6873 [Abstract] [Full Text]
Orci, L., Ravazzola, M., Volchuk, A., Engel, T., Gmachl, M., Amherdt, M., Perrelet, A., Sollner, T. H., Rothman, J. E. (2000). Anterograde flow of cargo across the Golgi stack potentially mediated via bidirectional "percolating" COPI vesicles. Proc. Natl. Acad. Sci. USA 97: 10400-10405 [Abstract] [Full Text]