Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues

doi:10.1083/jcb.133.1.43

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Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues

Y Ando-Akatsuka, M Saitou, T Hirase, M Kishi, A Sakakibara, M Itoh, S Yonemura, M Furuse and S Tsukita
Department of Cell Biology, Faculty of Medicine, Kyoto University, Japan.

Occludin has been identified from chick liver as a novel integral membrane protein localizing at tight junctions (Furuse, M., T. Hirase, M. Itoh, A. Nagafuchi, S. Yonemura, Sa. Tsukita, and Sh. Tsukita. 1993. J. Cell Biol. 123:1777-1788). To analyze and modulate the functions of tight junctions, it would be advantageous to know the mammalian homologues of occludin and their genes. Here we describe the nucleotide sequences of full length cDNAs encoding occludin of rat-kangaroo (potoroo), human, mouse, and dog. Rat-kangaroo occludin cDNA was prepared from RNA isolated from PtK2 cell culture, using a mAb against chicken occludin, whereas the others were amplified by polymerase chain reaction based on the sequence found around the human neuronal apoptosis inhibitory protein gene. The amino acid sequences of the three mammalian (human, murine, and canine) occludins were very closely related to each other (approximately 90% identity), whereas they diverged considerably from those of chicken and rat-kangaroo (approximately 50% identity). Implications of these data and novel experimental options in cell biological research are discussed.
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Blikslager, A. T., Moeser, A. J., Gookin, J. L., Jones, S. L., Odle, J. (2007). Restoration of Barrier Function in Injured Intestinal Mucosa. Physiol. Rev. 87: 545-564 [Abstract] [Full Text]
Moeser, A. J., Nighot, P. K., Engelke, K. J., Ueno, R., Blikslager, A. T. (2007). Recovery of mucosal barrier function in ischemic porcine ileum and colon is stimulated by a novel agonist of the ClC-2 chloride channel, lubiprostone. Am. J. Physiol. Gastrointest. Liver Physiol. 292: G647-G656 [Abstract] [Full Text]
Gorodeski, G. I. (2007). Estrogen Decrease in Tight Junctional Resistance Involves Matrix-Metalloproteinase-7-Mediated Remodeling of Occludin. Endocrinology 148: 218-231 [Abstract] [Full Text]
Zhu, L., Li, X., Zeng, R., Gorodeski, G. I. (2006). Changes in Tight Junctional Resistance of the Cervical Epithelium Are Associated with Modulation of Content and Phosphorylation of Occludin 65-Kilodalton and 50-Kilodalton Forms. Endocrinology 147: 977-989 [Abstract] [Full Text]
DeMaio, L., Rouhanizadeh, M., Reddy, S., Sevanian, A., Hwang, J., Hsiai, T. K. (2006). Oxidized phospholipids mediate occludin expression and phosphorylation in vascular endothelial cells. Am. J. Physiol. Heart Circ. Physiol. 290: H674-H683 [Abstract] [Full Text]
Mehta, D., Malik, A. B. (2006). Signaling Mechanisms Regulating Endothelial Permeability. Physiol. Rev. 86: 279-367 [Abstract] [Full Text]
Ikenouchi, J., Furuse, M., Furuse, K., Sasaki, H., Tsukita, S., Tsukita, S. (2005). Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells. JCB 171: 939-945 [Abstract] [Full Text]
Powell, K. (2005). Sticking it out with tight junctions. JCB 171: 916-917 [Full Text]
Gill, G A, Buda, A, Moorghen, M, Dettmar, P W, Pignatelli, M (2005). Characterisation of adherens and tight junctional molecules in normal animal larynx; determining a suitable model for studying molecular abnormalities in human laryngopharyngeal reflux. J. Clin. Pathol. 58: 1265-1270 [Abstract] [Full Text]
Nusrat, A., Brown, G. T., Tom, J., Drake, A., Bui, T. T.T., Quan, C., Mrsny, R. J. (2005). Multiple Protein Interactions Involving Proposed Extracellular Loop Domains of the Tight Junction Protein Occludin. Mol. Biol. Cell 16: 1725-1734 [Abstract] [Full Text]
Zeng, R., Li, X., Gorodeski, G. I. (2004). Estrogen Abrogates Transcervical Tight Junctional Resistance by Acceleration of Occludin Modulation. J. Clin. Endocrinol. Metab. 89: 5145-5155 [Abstract] [Full Text]
Bazzoni, G., Dejana, E. (2004). Endothelial Cell-to-Cell Junctions: Molecular Organization and Role in Vascular Homeostasis. Physiol. Rev. 84: 869-901 [Abstract] [Full Text]
Schneeberger, E. E., Lynch, R. D. (2004). The tight junction: a multifunctional complex. Am. J. Physiol. Cell Physiol. 286: C1213-C1228 [Abstract] [Full Text]
Turksen, K., Troy, T.-C. (2004). Barriers built on claudins. J. Cell Sci. 117: 2435-2447 [Abstract] [Full Text]
Schuster, M. K., Schmierer, B., Shkumatava, A., Kuchler, K. (2004). Activin A and Follicle-Stimulating Hormone Control Tight Junctions in Avian Granulosa Cells by Regulating Occludin Expression. Biol. Reprod. 70: 1493-1499 [Abstract] [Full Text]
Wang, X., Matsumoto, H., Zhao, X., Das, S. K., Paria, B. C. (2004). Embryonic signals direct the formation of tight junctional permeability barrier in the decidualizing stroma during embryo implantation. J. Cell Sci. 117: 53-62 [Abstract] [Full Text]
Peng, B.-H., Lee, J. C., Campbell, G. A. (2003). In Vitro Protein Complex Formation with Cytoskeleton-anchoring Domain of Occludin Identified by Limited Proteolysis. J. Biol. Chem. 278: 49644-49651 [Abstract] [Full Text]
Minagar, A., Alexander, J S. (2003). Blood-brain barrier disruption in multiple sclerosis. Mult Scler 9: 540-549 [Abstract]
Tavelin, S., Hashimoto, K., Malkinson, J., Lazorova, L., Toth, I., Artursson, P. (2003). A New Principle for Tight Junction Modulation Based on Occludin Peptides. Mol. Pharmacol. 64: 1530-1540 [Abstract] [Full Text]
Abe, T., Sugano, E., Saigo, Y., Tamai, M. (2003). Interleukin-1{beta} and Barrier Function of Retinal Pigment Epithelial Cells (ARPE-19): Aberrant Expression of Junctional Complex Molecules. IOVS 44: 4097-4104 [Abstract] [Full Text]
Sasaki, H., Matsui, C., Furuse, K., Mimori-Kiyosue, Y., Furuse, M., Tsukita, S. (2003). Dynamic behavior of paired claudin strands within apposing plasma membranes. Proc. Natl. Acad. Sci. USA 100: 3971-3976 [Abstract] [Full Text]
Lui, W.-Y., Mruk, D., Lee, W. M, Cheng, C. Y. (2003). Sertoli Cell Tight Junction Dynamics: Their Regulation During Spermatogenesis. Biol. Reprod. 68: 1087-1097 [Abstract] [Full Text]
Miller, D. J., Eckert, J. J., Lazzari, G., Duranthon-Richoux, V., Sreenan, J., Morris, D., Galli, C., Renard, J.-P., Fleming, T. P. (2003). Tight Junction Messenger RNA Expression Levels in Bovine Embryos are Dependent upon the Ability to Compact and In Vitro Culture Methods. Biol. Reprod. 68: 1394-1402 [Abstract] [Full Text]
Zhang, Y., Gu, Y., Lucas, M. J., Wang, Y. (2003). Antioxidant Superoxide Dismutase Attenuates Increased Endothelial Permeability Induced By Platelet-Activating Factor. Reproductive Sciences 10: 5-10 [Abstract]
Cheng, C. Y., Mruk, D. D. (2002). Cell Junction Dynamics in the Testis: Sertoli-Germ Cell Interactions and Male Contraceptive Development. Physiol. Rev. 82: 825-874 [Abstract] [Full Text]
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Nishimura, M., Kakizaki, M., Ono, Y., Morimoto, K., Takeuchi, M., Inoue, Y., Imai, T., Takai, Y. (2002). JEAP, a Novel Component of Tight Junctions in Exocrine Cells. J. Biol. Chem. 277: 5583-5587 [Abstract] [Full Text]
Ghassemifar, M. R., Sheth, B., Papenbrock, T., Leese, H. J., Houghton, F. D., Fleming, T. P. (2002). Occludin TM4-: an isoform of the tight junction protein present in primates lacking the fourth transmembrane domain. J. Cell Sci. 115: 3171-3180 [Abstract] [Full Text]
Xu, G. M., Sikaneta, T., Sullivan, B. M., Zhang, Q., Andreucci, M., Stehle, T., Drummond, I., Arnaout, M. A. (2001). Polycystin-1 Interacts with Intermediate Filaments. J. Biol. Chem. 276: 46544-46552 [Abstract] [Full Text]
Chung, N. P.Y., Mruk, D., Mo, M.-y., Lee, W. M., Cheng, C. Y. (2001). A 22-Amino Acid Synthetic Peptide Corresponding to the Second Extracellular Loop of Rat Occludin Perturbs the Blood-Testis Barrier and Disrupts Spermatogenesis Reversibly In Vivo. Biol. Reprod. 65: 1340-1351 [Abstract] [Full Text]
Gassler, N., Rohr, C., Schneider, A., Kartenbeck, J., Bach, A., Obermuller, N., Otto, H. F., Autschbach, F. (2001). Inflammatory bowel disease is associated with changes of enterocytic junctions. Am. J. Physiol. Gastrointest. Liver Physiol. 281: G216-G228 [Abstract] [Full Text]
DeMaio, L., Chang, Y. S., Gardner, T. W., Tarbell, J. M., Antonetti, D. A. (2001). Shear stress regulates occludin content and phosphorylation. Am. J. Physiol. Heart Circ. Physiol. 281: H105-H113 [Abstract] [Full Text]
MARINO, M., ANDREWS, D., BROWN, D., McCLUSKEY, R. T. (2001). Transcytosis of Retinol-Binding Protein across Renal Proximal Tubule Cells after Megalin (gp 330)-Mediated Endocytosis. J. Am. Soc. Nephrol. 12: 637-648 [Abstract] [Full Text]
Saitou, M., Furuse, M., Sasaki, H., Schulzke, J.-D., Fromm, M., Takano, H., Noda, T., Tsukita, S. (2000). Complex Phenotype of Mice Lacking Occludin, a Component of Tight Junction Strands. Mol. Biol. Cell 11: 4131-4142 [Abstract] [Full Text]
Marinò, M., Chiovato, L., Mitsiades, N., Latrofa, F., Andrews, D., Tseleni-Balafouta, S., Collins, A. B., Pinchera, A., McCluskey, R. T. (2000). Circulating Thyroglobulin Transcytosed by Thyroid Cells Is Complexed with Secretory Components of Its Endocytic Receptor Megalin. J. Clin. Endocrinol. Metab. 85: 3458-3467 [Abstract] [Full Text]
Tsukita, S., Furuse, M. (2000). Pores in the Wall: Claudins Constitute Tight Junction Strands Containing Aqueous Pores. JCB 149: 13-16 [Full Text]
Marino, M., Zheng, G., Chiovato, L., Pinchera, A., Brown, D., Andrews, D., McCluskey, R. T. (2000). Role of Megalin (gp330) in Transcytosis of Thyroglobulin by Thyroid Cells. A NOVEL FUNCTION IN THE CONTROL OF THYROID HORMONE RELEASE. J. Biol. Chem. 275: 7125-7137 [Abstract] [Full Text]
Chen, Y.-h., Lu, Q., Schneeberger, E. E., Goodenough, D. A. (2000). Restoration of Tight Junction Structure and Barrier Function by Down-Regulation of the Mitogen-activated Protein Kinase Pathway in Ras-transformed Madin-Darby Canine Kidney Cells. Mol. Biol. Cell 11: 849-862 [Abstract] [Full Text]
Muresan, Z., Paul, D. L., Goodenough, D. A. (2000). Occludin 1B, a Variant of the Tight Junction Protein Occludin. Mol. Biol. Cell 11: 627-634 [Abstract] [Full Text]
McCarthy, K., Francis, S., McCormack, J., Lai, J, Rogers, R., Skare, I., Lynch, R., Schneeberger, E. (2000). Inducible expression of claudin-1-myc but not occludin-VSV-G results in aberrant tight junction strand formation in MDCK cells. J. Cell Sci. 113: 3387-3398 [Abstract]
Clarke, H, Soler, A., Mullin, J. (2000). Protein kinase C activation leads to dephosphorylation of occludin and tight junction permeability increase in LLC-PK1 epithelial cell sheets. J. Cell Sci. 113: 3187-3196 [Abstract]
Mankertz, J, Tavalali, S, Schmitz, H, Mankertz, A, Riecken, E., Fromm, M, Schulzke, J. (2000). Expression from the human occludin promoter is affected by tumor necrosis factor alpha and interferon gamma. J. Cell Sci. 113: 2085-2090 [Abstract]
Sheth, B, Moran, B, Anderson, J., Fleming, T. (2000). Post-translational control of occludin membrane assembly in mouse trophectoderm: a mechanism to regulate timing of tight junction biogenesis and blastocyst formation. Development 127: 831-840 [Abstract]
Itoh, M., Furuse, M., Morita, K., Kubota, K., Saitou, M., Tsukita, S. (1999). Direct Binding of Three Tight Junction-Associated Maguks, Zo-1, Zo-2, and Zo-3, with the Cooh Termini of Claudins. JCB 147: 1351-1363 [Abstract] [Full Text]
Furuse, M., Sasaki, H., Tsukita, S. (1999). Manner of Interaction of Heterogeneous Claudin Species within and between Tight Junction Strands. JCB 147: 891-903 [Abstract] [Full Text]
Morita, K., Sasaki, H., Furuse, M., Tsukita, S. (1999). Endothelial Claudin: Claudin-5/Tmvcf Constitutes Tight Junction Strands in Endothelial Cells. JCB 147: 185-194 [Abstract] [Full Text]
Sonoda, N., Furuse, M., Sasaki, H., Yonemura, S., Katahira, J., Horiguchi, Y., Tsukita, S. (1999). Clostridium perfringens Enterotoxin Fragment Removes Specific Claudins from Tight Junction Strands: Evidence for Direct Involvement of Claudins in Tight Junction Barrier. JCB 147: 195-204 [Abstract] [Full Text]
Ikeda, W., Nakanishi, H., Miyoshi, J., Mandai, K., Ishizaki, H., Tanaka, M., Togawa, A., Takahashi, K., Nishioka, H., Yoshida, H., Mizoguchi, A., Nishikawa, S.-i., Takai, Y. (1999). Afadin: A Key Molecule Essential for Structural Organization of Cell-Cell Junctions of Polarized Epithelia during Embryogenesis. JCB 146: 1117-1132 [Abstract] [Full Text]
Antonetti, D. A., Barber, A. J., Hollinger, L. A., Wolpert, E. B., Gardner, T. W. (1999). Vascular Endothelial Growth Factor Induces Rapid Phosphorylation of Tight Junction Proteins Occludin and Zonula Occluden 1. A POTENTIAL MECHANISM FOR VASCULAR PERMEABILITY IN DIABETIC RETINOPATHY AND TUMORS. J. Biol. Chem. 274: 23463-23467 [Abstract] [Full Text]
Mitic, L. L., Schneeberger, E. E., Fanning, A. S., Anderson, J. M. (1999). Connexin-Occludin Chimeras Containing the Zo-Binding Domain of Occludin Localize at Mdck Tight Junctions and Nrk Cell Contacts. JCB 146: 683-693 [Abstract] [Full Text]
Cyr, D. G., Hermo, L., Egenberger, N., Mertineit, C., Trasler, J. M., Laird, D. W. (1999). Cellular Immunolocalization of Occludin during Embryonic and Postnatal Development of the Mouse Testis and Epididymis. Endocrinology 140: 3815-3825 [Abstract] [Full Text]
Morita, K., Sasaki, H., Fujimoto, K., Furuse, M., Tsukita, S. (1999). Claudin-11/OSP-based Tight Junctions of Myelin Sheaths in Brain and Sertoli Cells in Testis. JCB 145: 579-588 [Abstract] [Full Text]
Mandai, K., Nakanishi, H., Satoh, A., Takahashi, K., Satoh, K., Nishioka, H., Mizoguchi, A., Takai, Y. (1999). Ponsin/SH3P12: An l-Afadin- and Vinculin-binding Protein Localized at Cell-Cell and Cell-Matrix Adherens Junctions. JCB 144: 1001-1018 [Abstract] [Full Text]
Itoh, M., Morita, K., Tsukita, S. (1999). Characterization of ZO-2 as a MAGUK Family Member Associated with Tight as well as Adherens Junctions with a Binding Affinity to Occludin and alpha �Catenin. J. Biol. Chem. 274: 5981-5986 [Abstract] [Full Text]
Morita, K., Furuse, M., Fujimoto, K., Tsukita, S. (1999). Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands. Proc. Natl. Acad. Sci. USA 96: 511-516 [Abstract] [Full Text]
Wachtel, M, Frei, K, Ehler, E, Fontana, A, Winterhalter, K, Gloor, S. (1999). Occludin proteolysis and increased permeability in endothelial cells through tyrosine phosphatase inhibition. J. Cell Sci. 112: 4347-4356 [Abstract]
Bamforth, S., Kniesel, U, Wolburg, H, Engelhardt, B, Risau, W (1999). A dominant mutant of occludin disrupts tight junction structure and function. J. Cell Sci. 112: 1879-1888 [Abstract]
Furuse, M., Sasaki, H., Fujimoto, K., Tsukita, S. (1998). A Single Gene Product, Claudin-1 or -2, Reconstitutes Tight Junction Strands and Recruits Occludin in Fibroblasts. JCB 143: 391-401 [Abstract] [Full Text]
Furuse, M., Fujita, K., Hiiragi, T., Fujimoto, K., Tsukita, S. (1998). Claudin-1 and -2: Novel Integral Membrane Proteins Localizing at Tight Junctions with No Sequence Similarity to Occludin. JCB 141: 1539-1550 [Abstract] [Full Text]
Moroi, S., Saitou, M., Fujimoto, K., Sakakibara, A., Furuse, M., Yoshida, O., Tsukita, S. (1998). Occludin is concentrated at tight junctions of mouse/rat but not human/guinea pig Sertoli cells in testes. Am. J. Physiol. Cell Physiol. 274: C1708-C1717 [Abstract] [Full Text]
Saitou, M., Fujimoto, K., Doi, Y., Itoh, M., Fujimoto, T., Furuse, M., Takano, H., Noda, T., Tsukita, S. (1998). Occludin-deficient Embryonic Stem Cells Can Differentiate into Polarized Epithelial Cells Bearing Tight Junctions. JCB 141: 397-408 [Abstract] [Full Text]
Balda, M., Matter, K (1998). Tight junctions. J. Cell Sci. 111: 541-547 [Abstract]
Matter, K, Balda, M. (1998). Biogenesis of tight junctions: the C-terminal domain of occludin mediates basolateral targeting. J. Cell Sci. 111: 511-519 [Abstract]
Denker, B. M., Nigam, S. K. (1998). Molecular structure and assembly of the tight junction. Am. J. Physiol. Renal Physiol. 274: F1-F9 [Abstract] [Full Text]
Chen, Y.-h., Merzdorf, C., Paul, D. L., Goodenough, D. A. (1997). COOH Terminus of Occludin Is Required for Tight Junction Barrier Function in Early Xenopus Embryos. JCB 138: 891-899 [Abstract] [Full Text]
Itoh, M., Nagafuchi, A., Moroi, S., Tsukita, S. (1997). Involvement of ZO-1 in Cadherin-based Cell Adhesion through Its Direct Binding to {alpha} Catenin and Actin Filaments. JCB 138: 181-192 [Abstract] [Full Text]
Sakakibara, A., Furuse, M., Saitou, M., Ando-Akatsuka, Y., Tsukita, S. (1997). Possible Involvement of Phosphorylation of Occludin in Tight Junction Formation. JCB 137: 1393-1401 [Abstract] [Full Text]
Wong, V., Gumbiner, B. M. (1997). A Synthetic Peptide Corresponding to the Extracellular Domain of Occludin Perturbs the Tight Junction Permeability Barrier. JCB 136: 399-409 [Abstract] [Full Text]
Cordenonsi, M, Mazzon, E, De Rigo, L, Baraldo, S, Meggio, F, Citi, S (1997). Occludin dephosphorylation in early development of Xenopus laevis. J. Cell Sci. 110: 3131-3139 [Abstract]
Hirase, T, Staddon, J., Saitou, M, Ando-Akatsuka, Y, Itoh, M, Furuse, M, Fujimoto, K, Tsukita, S, Rubin, L. (1997). Occludin as a possible determinant of tight junction permeability in endothelial cells. J. Cell Sci. 110: 1603-1613 [Abstract]
Van Itallie, C., Anderson, J. (1997). Occludin confers adhesiveness when expressed in fibroblasts. J. Cell Sci. 110: 1113-1121 [Abstract]
McCarthy, K., Skare, I., Stankewich, M., Furuse, M, Tsukita, S, Rogers, R., Lynch, R., Schneeberger, E. (1996). Occludin is a functional component of the tight junction. J. Cell Sci. 109: 2287-2298 [Abstract]
Nusrat, A., Chen, J. A., Foley, C. S., Liang, T. W., Tom, J., Cromwell, M., Quan, C., Mrsny, R. J. (2000). The Coiled-coil Domain of Occludin Can Act to Organize Structural and Functional Elements of the Epithelial Tight Junction. J. Biol. Chem. 275: 29816-29822 [Abstract] [Full Text]
Mattagajasingh, S. N., Huang, S.-C., Hartenstein, J. S., Benz, E. J. Jr. (2000). Characterization of the Interaction between Protein 4.1R and ZO-2. A POSSIBLE LINK BETWEEN THE TIGHT JUNCTION AND THE ACTIN CYTOSKELETON. J. Biol. Chem. 275: 30573-30585 [Abstract] [Full Text]
Nishiyama, R., Sakaguchi, T., Kinugasa, T., Gu, X., MacDermott, R. P., Podolsky, D. K., Reinecker, H.-C. (2001). Interleukin-2 Receptor beta Subunit-dependent and -independent Regulation of Intestinal Epithelial Tight Junctions. J. Biol. Chem. 276: 35571-35580 [Abstract] [Full Text]