Caveolin-3 Associates with Developing T-tubules during Muscle Differentiation

doi:10.1083/jcb.136.1.137

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© The Rockefeller University Press, 0021-9525/1997//137 $5.00
The Journal of Cell Biology, Volume 136, Number 1, , 1997 137-154

Article

Caveolin-3 Associates with Developing T-tubules during Muscle Differentiation

Robert G. Parton^*, Michael Way, Natasha Zorzi^*, and Espen Stang^*

^* Centre for Microscopy and Microanalysis, Department of Physiology and Pharmacology, and Centre for Molecular and Cellular Biology, University of Queensland, Queensland 4072, Brisbane, Australia; and European Molecular Biology Laboratory, D69012 Heidelberg, Germany

Caveolae, flask-shaped invaginations of the plasma membrane,are particularly abundant in muscle cells. We have recentlycloned a muscle-specific caveolin, termed caveolin-3, whichis expressed in differentiated muscle cells. Specific antibodiesto caveolin-3 were generated and used to characterize the distributionof caveolin-3 in adult and differentiating muscle. In fully differentiated skeletal muscle, caveolin-3 was shown to beassociated exclusively with sarcolemmal caveolae. Localizationof caveolin-3 during differentiation of primary cultured musclecells and development of mouse skeletal muscle in vivo suggestedthat caveolin-3 is transiently associated with an internal membranesystem. These elements were identified as developing transverse-(T)-tubulesby double-labeling with antibodies to the ${alpha}$ ₁ subunit of thedihydropyridine receptor in C2C12 cells. Ultrastructural analysisof the caveolin-3– labeled elements showed an associationof caveolin-3 with elaborate networks of interconnected caveolae, which penetrated the depths of the muscle fibers. These elements,which formed regular reticular structures, were shown to besurface-connected by labeling with cholera toxin conjugates.The results suggest that caveolin-3 transiently associates withT-tubules during development and may be involved in the earlydevelopment of the T-tubule system in muscle.

Abbreviations used in this paper: CT-B, cholera toxin binding subunit; DIG, detergent-insoluble glycosphingolipid-enriched complex; DHPR, dihydropyridine receptor; T-tubule, transverse-tubule.

Address all correspondence to R.G. Parton, Centre for Microscopyand Microanalysis, University of Queensland, Queensland 4072,Australia. Tel.: 61-7-3365-6468. Fax: 61-7-3365-4422. e-mail:R.Parton{at}mailbox.uq.oz.au

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Boulware, M. I., Kordasiewicz, H., Mermelstein, P. G. (2007). Caveolin Proteins Are Essential for Distinct Effects of Membrane Estrogen Receptors in Neurons. J. Neurosci. 27: 9941-9950 [Abstract] [Full Text]
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Klinge, L., Laval, S., Keers, S., Haldane, F., Straub, V., Barresi, R., Bushby, K. (2007). From T-tubule to sarcolemma: damage-induced dysferlin translocation in early myogenesis. FASEB J. 21: 1768-1776 [Abstract] [Full Text]
Suchyna, T. M., Sachs, F. (2007). Mechanosensitive channel properties and membrane mechanics in mouse dystrophic myotubes. J. Physiol. 581: 369-387 [Abstract] [Full Text]
Patel, H. H., Tsutsumi, Y. M., Head, B. P., Niesman, I. R., Jennings, M., Horikawa, Y., Huang, D., Moreno, A. L., Patel, P. M., Insel, P. A., Roth, D. M. (2007). Mechanisms of cardiac protection from ischemia/reperfusion injury: a role for caveolae and caveolin-1. FASEB J. 21: 1565-1574 [Abstract] [Full Text]
Couchoux, H., Allard, B., Legrand, C., Jacquemond, V., Berthier, C. (2007). Loss of caveolin-3 induced by the dystrophy-associated P104L mutation impairs L-type calcium channel function in mouse skeletal muscle cells. J. Physiol. 580: 745-754 [Abstract] [Full Text]
Head, B. P., Patel, H. H., Roth, D. M., Murray, F., Swaney, J. S., Niesman, I. R., Farquhar, M. G., Insel, P. A. (2006). Microtubules and Actin Microfilaments Regulate Lipid Raft/Caveolae Localization of Adenylyl Cyclase Signaling Components. J. Biol. Chem. 281: 26391-26399 [Abstract] [Full Text]
Parton, R. G., Hanzal-Bayer, M., Hancock, J. F. (2006). Biogenesis of caveolae: a structural model for caveolin-induced domain formation.. J. Cell Sci. 119: 787-796 [Abstract] [Full Text]
Hernandez-Deviez, D. J., Martin, S., Laval, S. H., Lo, H. P., Cooper, S. T., North, K. N., Bushby, K., Parton, R. G. (2006). Aberrant dysferlin trafficking in cells lacking caveolin or expressing dystrophy mutants of caveolin-3. Hum Mol Genet 15: 129-142 [Abstract] [Full Text]
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Capozza, F., Cohen, A. W., Cheung, M. W.-C., Sotgia, F., Schubert, W., Battista, M., Lee, H., Frank, P. G., Lisanti, M. P. (2005). Muscle-specific interaction of caveolin isoforms: differential complex formation between caveolins in fibroblastic vs. muscle cells. Am. J. Physiol. Cell Physiol. 288: C677-C691 [Abstract] [Full Text]
Pietiainen, V., Marjomaki, V., Upla, P., Pelkmans, L., Helenius, A., Hyypia, T. (2004). Echovirus 1 Endocytosis into Caveosomes Requires Lipid Rafts, Dynamin II, and Signaling Events. Mol. Biol. Cell 15: 4911-4925 [Abstract] [Full Text]
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Woodman, S. E., Sotgia, F., Galbiati, F., Minetti, C., Lisanti, M. P. (2004). Caveolinopathies: Mutations in caveolin-3 cause four distinct autosomal dominant muscle diseases. Neurology 62: 538-543 [Abstract] [Full Text]
Gaudreault, S. B., Chabot, C., Gratton, J.-P., Poirier, J. (2004). The Caveolin Scaffolding Domain Modifies 2-Amino-3-hydroxy-5-methyl-4-isoxazole Propionate Receptor Binding Properties by Inhibiting Phospholipase A2 Activity. J. Biol. Chem. 279: 356-362 [Abstract] [Full Text]
Hnasko, R., Lisanti, M. P. (2003). The Biology of Caveolae: Lessons from Caveolin Knockout Mice and Implications for Human Disease. Mol. Interv. 3: 445-464 [Abstract] [Full Text]
Smythe, G. M., Eby, J. C., Disatnik, M.-H., Rando, T. A. (2003). A caveolin-3 mutant that causes limb girdle muscular dystrophy type 1C disrupts Src localization and activity and induces apoptosis in skeletal myotubes. J. Cell Sci. 116: 4739-4749 [Abstract] [Full Text]
Sotgia, F., Woodman, S. E., Bonuccelli, G., Capozza, F., Minetti, C., Scherer, P. E., Lisanti, M. P. (2003). Phenotypic behavior of caveolin-3 R26Q, a mutant associated with hyperCKemia, distal myopathy, and rippling muscle disease. Am. J. Physiol. Cell Physiol. 285: C1150-C1160 [Abstract] [Full Text]
Carlson, B. M., Carlson, J. A., Dedkov, E. I., McLennan, I. S. (2003). Concentration of Caveolin-3 at the Neuromuscular Junction in Young and Old Rat Skeletal Muscle Fibers. J. Histochem. Cytochem. 51: 1113-1118 [Abstract] [Full Text]
Koga, A., Oka, N., Kikuchi, T., Miyazaki, H., Kato, S., Imaizumi, T. (2003). Adenovirus-Mediated Overexpression of Caveolin-3 Inhibits Rat Cardiomyocyte Hypertrophy. Hypertension 42: 213-219 [Abstract] [Full Text]
Morrow, I. C., Rea, S., Martin, S., Prior, I. A., Prohaska, R., Hancock, J. F., James, D. E., Parton, R. G. (2002). Flotillin-1/Reggie-2 Traffics to Surface Raft Domains via a Novel Golgi-independent Pathway. IDENTIFICATION OF A NOVEL MEMBRANE TARGETING DOMAIN AND A ROLE FOR PALMITOYLATION. J. Biol. Chem. 277: 48834-48841 [Abstract] [Full Text]
Woodman, S. E., Park, D. S., Cohen, A. W., Cheung, M. W.-C., Chandra, M., Shirani, J., Tang, B., Jelicks, L. A., Kitsis, R. N., Christ, G. J., Factor, S. M., Tanowitz, H. B., Lisanti, M. P. (2002). Caveolin-3 Knock-out Mice Develop a Progressive Cardiomyopathy and Show Hyperactivation of the p42/44 MAPK Cascade. J. Biol. Chem. 277: 38988-38997 [Abstract] [Full Text]
Razani, B., Woodman, S. E., Lisanti, M. P. (2002). Caveolae: From Cell Biology to Animal Physiology. Pharmacol. Rev. 54: 431-467 [Abstract] [Full Text]
Lee, E., Marcucci, M., Daniell, L., Pypaert, M., Weisz, O. A., Ochoa, G.-C., Farsad, K., Wenk, M. R., De Camilli, P. (2002). Amphiphysin 2 (Bin1) and T-Tubule Biogenesis in Muscle. Science 297: 1193-1196 [Abstract] [Full Text]
Brown, G., Rixon, H. W. McL., Sugrue, R. J. (2002). Respiratory syncytial virus assembly occurs in GM1-rich regions of the host-cell membrane and alters the cellular distribution of tyrosine phosphorylated caveolin-1. J. Gen. Virol. 83: 1841-1850 [Abstract] [Full Text]
Sotgia, F., Razani, B., Bonuccelli, G., Schubert, W., Battista, M., Lee, H., Capozza, F., Schubert, A. L., Minetti, C., Buckley, J. T., Lisanti, M. P. (2002). Intracellular Retention of Glycosylphosphatidyl Inositol-Linked Proteins in Caveolin-Deficient Cells. Mol. Cell. Biol. 22: 3905-3926 [Abstract] [Full Text]
Carozzi, A. J., Roy, S., Morrow, I. C., Pol, A., Wyse, B., Clyde-Smith, J., Prior, I. A., Nixon, S. J., Hancock, J. F., Parton, R. G. (2002). Inhibition of Lipid Raft-dependent Signaling by a Dystrophy-associated Mutant of Caveolin-3. J. Biol. Chem. 277: 17944-17949 [Abstract] [Full Text]
Feron, O., Kelly, R. A. (2002). Gaining Respectability: Membrane-Delimited, Caveolar-Restricted Activation of Ion Channels. Circ. Res. 90: 369-370 [Full Text]
Minetti, C., Bado, M., Broda, P., Sotgia, F., Bruno, C., Galbiati, F., Volonte, D., Lucania, G., Pavan, A., Bonilla, E., Lisanti, M. P., Cordone, G. (2002). Impairment of Caveolae Formation and T-System Disorganization in Human Muscular Dystrophy with Caveolin-3 Deficiency. Am. J. Pathol. 160: 265-270 [Abstract] [Full Text]
Wunderlich, W., Fialka, I., Teis, D., Alpi, A., Pfeifer, A., Parton, R. G., Lottspeich, F., Huber, L. A. (2001). A Novel 14-Kilodalton Protein Interacts with the Mitogen-Activated Protein Kinase Scaffold Mp1 on a Late Endosomal/Lysosomal Compartment. JCB 152: 765-776 [Abstract] [Full Text]
La Fontaine, S., Theophilos, M. B., Firth, S. D., Gould, R., Parton, R. G., Mercer, J. F.B. (2001). Effect of the toxic milk mutation (tx) on the function and intracellular localization of Wnd, the murine homologue of the Wilson copper ATPase. Hum Mol Genet 10: 361-370 [Abstract] [Full Text]
Li, W., Liu, P, Pilcher, B., Anderson, R. (2001). Cell-specific targeting of caveolin-1 to caveolae, secretory vesicles, cytoplasm or mitochondria. J. Cell Sci. 114: 1397-1408 [Abstract]
Ginkel, L. M., Wordeman, L. (2000). Expression and Partial Characterization of Kinesin-related Proteins in Differentiating and Adult Skeletal Muscle. Mol. Biol. Cell 11: 4143-4158 [Abstract] [Full Text]
Simons, M., Kramer, E.-M., Thiele, C., Stoffel, W., Trotter, J. (2000). Assembly of Myelin by Association of Proteolipid Protein with Cholesterol- and Galactosylceramide-Rich Membrane Domains. JCB 151: 143-154 [Abstract] [Full Text]
Doyle, D. D., Goings, G., Upshaw-Earley, J., Ambler, S. K., Mondul, A., Palfrey, H. C., Page, E. (2000). Dystrophin Associates With Caveolae of Rat Cardiac Myocytes : Relationship to Dystroglycan. Circ. Res. 87: 480-488 [Abstract] [Full Text]
Mullock, B. M., Smith, C. W., Ihrke, G., Bright, N. A., Lindsay, M., Parkinson, E. J., Brooks, D. A., Parton, R. G., James, D. E., Luzio, J. P., Piper, R. C. (2000). Syntaxin 7 Is Localized to Late Endosome Compartments, Associates with Vamp 8, and Is Required for Late Endosome-Lysosome Fusion. Mol. Biol. Cell 11: 3137-3153 [Abstract] [Full Text]
Haynes, W. J., Ling, K.-Y., Preston, R. R., Saimi, Y., Kung, C. (2000). The Cloning and Molecular Analysis of pawn-B in Paramecium tetraurelia. Genetics 155: 1105-1117 [Abstract] [Full Text]
Apolloni, A., Prior, I. A., Lindsay, M., Parton, R. G., Hancock, J. F. (2000). H-ras but Not K-ras Traffics to the Plasma Membrane through the Exocytic Pathway. Mol. Cell. Biol. 20: 2475-2487 [Abstract] [Full Text]
Razani, B, Schlegel, A, Lisanti, M. (2000). Caveolin proteins in signaling, oncogenic transformation and muscular dystrophy. J. Cell Sci. 113: 2103-2109 [Abstract]
Smart, E. J., Graf, G. A., McNiven, M. A., Sessa, W. C., Engelman, J. A., Scherer, P. E., Okamoto, T., Lisanti, M. P. (1999). Caveolins, Liquid-Ordered Domains, and Signal Transduction. Mol. Cell. Biol. 19: 7289-7304 [Full Text]
Luetterforst, R., Stang, E., Zorzi, N., Carozzi, A., Way, M., Parton, R. G. (1999). Molecular Characterization of Caveolin Association with the Golgi Complex: Identification of a Cis-Golgi Targeting Domain in the Caveolin Molecule. JCB 145: 1443-1459 [Abstract] [Full Text]
Graf, G. A., Connell, P. M., van der Westhuyzen, D. R., Smart, E. J. (1999). The Class B, Type I Scavenger Receptor Promotes the Selective Uptake of High Density Lipoprotein Cholesterol Ethers into Caveolae. J. Biol. Chem. 274: 12043-12048 [Abstract] [Full Text]
Sincock, P., Fitter, S, Parton, R., Berndt, M., Gamble, J., Ashman, L. (1999). PETA-3/CD151, a member of the transmembrane 4 superfamily, is localised to the plasma membrane and endocytic system of endothelial cells, associates with multiple integrins and modulates cell function. J. Cell Sci. 112: 833-844 [Abstract]
Shaul, P. W., Anderson, R. G.�W. (1998). Role of plasmalemmal caveolae in signal transduction. Am. J. Physiol. Lung Cell. Mol. Physiol. 275: L843-L851 [Abstract] [Full Text]
Zeng, Q., Subramaniam, V. N., Wong, S. H., Tang, B. L., Parton, R. G., Rea, S., James, D. E., Hong, W. (1998). A Novel Synaptobrevin/VAMP Homologous Protein (VAMP5) Is Increased during In Vitro Myogenesis and Present in the Plasma Membrane. Mol. Biol. Cell 9: 2423-2437 [Abstract] [Full Text]
Okamoto, T., Schlegel, A., Scherer, P. E., Lisanti, M. P. (1998). Caveolins, a Family of Scaffolding Proteins for Organizing "Preassembled Signaling Complexes" at the Plasma Membrane. J. Biol. Chem. 273: 5419-5422 [Full Text]
Vogel, U, Sandvig, K, van Deurs, B (1998). Expression of caveolin-1 and polarized formation of invaginated caveolae in Caco-2 and MDCK II cells. J. Cell Sci. 111: 825-832 [Abstract]
Cameron, P. L., Ruffin, J. W., Bollag, R., Rasmussen, H., Cameron, R. S. (1997). Identification of Caveolin and Caveolin-Related Proteins in the Brain. J. Neurosci. 17: 9520-9535 [Abstract] [Full Text]
Oka, N., Asai, K., Kudej, R. K., Edwards, J. G., Toya, Y., Schwencke, C., Vatner, D. E., Vatner, S. F., Ishikawa, Y. (1997). Downregulation of caveolin by chronic beta -adrenergic receptor stimulation in mice. Am. J. Physiol. Cell Physiol. 273: C1957-C1962 [Abstract] [Full Text]
Feron, O., Smith, T. W., Michel, T., Kelly, R. A. (1997). Dynamic Targeting of the Agonist-stimulated m2 Muscarinic Acetylcholine Receptor to Caveolae in Cardiac Myocytes. J. Biol. Chem. 272: 17744-17748 [Abstract] [Full Text]
Schubert, W., Frank, P. G., Razani, B., Park, D. S., Chow, C.-W., Lisanti, M. P. (2001). Caveolae-deficient Endothelial Cells Show Defects in the Uptake and Transport of Albumin in Vivo. J. Biol. Chem. 276: 48619-48622 [Abstract] [Full Text]
Biederer, C. H., Ries, S. J., Moser, M., Florio, M., Israel, M. A., McCormick, F., Buettner, R. (2000). The Basic Helix-Loop-Helix Transcription Factors Myogenin and Id2 Mediate Specific Induction of Caveolin-3 Gene Expression during Embryonic Development. J. Biol. Chem. 275: 26245-26251 [Abstract] [Full Text]
Galbiati, F., Engelman, J. A., Volonte, D., Zhang, X. L., Minetti, C., Li, M., Hou, H. Jr., Kneitz, B., Edelmann, W., Lisanti, M. P. (2001). Caveolin-3 Null Mice Show a Loss of Caveolae, Changes in the Microdomain Distribution of the Dystrophin-Glycoprotein Complex, and T-tubule Abnormalities. J. Biol. Chem. 276: 21425-21433 [Abstract] [Full Text]
Dermine, J.-F., Duclos, S., Garin, J., St-Louis, F., Rea, S., Parton, R. G., Desjardins, M. (2001). Flotillin-1-enriched Lipid Raft Domains Accumulate on Maturing Phagosomes. J. Biol. Chem. 276: 18507-18512 [Abstract] [Full Text]