Home | Help | Feedback | Subscriptions | Archive | Search | Table of Contents

This Article Full Text Full Text (PDF, 183K) PPT slides of all figures Alert me when this article is cited Citation Map Services Email this article Similar articles in this journal Similar articles in PubMed Alert me to new content in the JCB Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Olazabal, I. M. Articles by Machesky, L. M. Search for Related Content PubMed PubMed Citation Articles by Olazabal, I. M. Articles by Machesky, L. M. Social Bookmarking                            What's this?

© The Rockefeller University Press, 0021-9525/2001/8/679 $5.00
The Journal of Cell Biology, Volume 154, Number 4, August 20, 2001 679-682

Abp1p and cortactin, new "hand-holds" for actin

School of Biosciences, Division of Molecular Cell Biology, University of Birmingham, Birmingham B15 2TT, United Kingdom

Address correspondence to Laura Machesky, Division of Molecular and Cellular Biology, University of Birmingham, School of Biosciences, Birmingham B15 2TT, UK. Tel.: 44-121-414-2504. Fax: 44-121-414-5925. E-mail: l.m.machesky{at}bham.ac.uk

Abstract

Recently, two new ligands of the Arp2/3 complex have been described that may shed light on the way cells organize complex networks of actin in response to signals. Abp1p, a yeast protein involved in endocytosis, and cortactin, a mammalian src substrate, both enhance the ability of the Arp2/3 complex to assemble branched actin filament networks.

CiteULike

Complore

Connotea

Del.icio.us

Digg

Facebook

Reddit

Technorati

Twitter

This article has been cited by other articles:

• Wang, W., Chen, L., Ding, Y., Jin, J., Liao, K. (2008). Centrosome separation driven by actin-microfilaments during mitosis is mediated by centrosome-associated tyrosine-phosphorylated cortactin. J. Cell Sci. 121: 1334-1343 [Abstract] [Full Text]  
• Ayala, I., Baldassarre, M., Giacchetti, G., Caldieri, G., Tete, S., Luini, A., Buccione, R. (2008). Multiple regulatory inputs converge on cortactin to control invadopodia biogenesis and extracellular matrix degradation. J. Cell Sci. 121: 369-378 [Abstract] [Full Text]  
• Guo, T., Gregg, C., Boukh-Viner, T., Kyryakov, P., Goldberg, A., Bourque, S., Banu, F., Haile, S., Milijevic, S., San, K. H. Y., Solomon, J., Wong, V., Titorenko, V. I. (2007). A signal from inside the peroxisome initiates its division by promoting the remodeling of the peroxisomal membrane. JCB 177: 289-303 [Abstract] [Full Text]  
• Ikeda, K., Kundu, R. K., Ikeda, S., Kobara, M., Matsubara, H., Quertermous, T. (2006). Glia Maturation Factor-{gamma} Is Preferentially Expressed in Microvascular Endothelial and Inflammatory Cells and Modulates Actin Cytoskeleton Reorganization. Circ. Res. 99: 424-433 [Abstract] [Full Text]  
• Webb, B. A., Eves, R., Crawley, S. W., Zhou, S., Cote, G. P., Mak, A. S. (2005). PAK1 induces podosome formation in A7r5 vascular smooth muscle cells in a PAK-interacting exchange factor-dependent manner. Am. J. Physiol. Cell Physiol. 289: C898-C907 [Abstract] [Full Text]  
• Lambotin, M., Hoffmann, I., Laran-Chich, M.-P., Nassif, X., Couraud, P. O., Bourdoulous, S. (2005). Invasion of endothelial cells by Neisseria meningitidis requires cortactin recruitment by a phosphoinositide-3-kinase/Rac1 signalling pathway triggered by the lipo-oligosaccharide. J. Cell Sci. 118: 3805-3816 [Abstract] [Full Text]  
• Quintero-Monzon, O., Rodal, A. A., Strokopytov, B., Almo, S. C., Goode, B. L. (2005). Structural and Functional Dissection of the Abp1 ADFH Actin-binding Domain Reveals Versatile In Vivo Adapter Functions. Mol. Biol. Cell 16: 3128-3139 [Abstract] [Full Text]  
• Nesti, E., Everill, B., Morielli, A. D. (2004). Endocytosis as a Mechanism for Tyrosine Kinase-dependent Suppression of a Voltage-gated Potassium Channel. Mol. Biol. Cell 15: 4073-4088 [Abstract] [Full Text]  
• Bougneres, L., Girardin, S. E., Weed, S. A., Karginov, A. V., Olivo-Marin, J.-C., Parsons, J. T., Sansonetti, P. J., Van Nhieu, G. T. (2004). Cortactin and Crk cooperate to trigger actin polymerization during Shigella invasion of epithelial cells. JCB 166: 225-235 [Abstract] [Full Text]  
• Kessels, M. M., Qualmann, B. (2004). The syndapin protein family: linking membrane trafficking with the cytoskeleton. J. Cell Sci. 117: 3077-3086 [Abstract] [Full Text]  
• Le Bras, S., Foucault, I., Foussat, A., Brignone, C., Acuto, O., Deckert, M. (2004). Recruitment of the Actin-binding Protein HIP-55 to the Immunological Synapse Regulates T Cell Receptor Signaling and Endocytosis. J. Biol. Chem. 279: 15550-15560 [Abstract] [Full Text]  
• Helwani, F. M., Kovacs, E. M., Paterson, A. D., Verma, S., Ali, R. G., Fanning, A. S., Weed, S. A., Yap, A. S. (2004). Cortactin is necessary for E-cadherin-mediated contact formation and actin reorganization. JCB 164: 899-910 [Abstract] [Full Text]  
• Qualmann, B., Boeckers, T. M., Jeromin, M., Gundelfinger, E. D., Kessels, M. M. (2004). Linkage of the Actin Cytoskeleton to the Postsynaptic Density via Direct Interactions of Abp1 with the ProSAP/Shank Family. J. Neurosci. 24: 2481-2495 [Abstract] [Full Text]  
• Burgstaller, G., Gimona, M. (2004). Actin cytoskeleton remodelling via local inhibition of contractility at discrete microdomains. J. Cell Sci. 117: 223-231 [Abstract] [Full Text]  
• Hasson, T. (2003). Myosin VI: two distinct roles in endocytosis. J. Cell Sci. 116: 3453-3461 [Abstract] [Full Text]  
• Hou, P., Estrada, L., Kinley, A. W., Parsons, J. T., Vojtek, A. B., Gorski, J. L. (2003). Fgd1, the Cdc42 GEF responsible for Faciogenital Dysplasia, directly interacts with cortactin and mAbp1 to modulate cell shape. Hum Mol Genet 12: 1981-1993 [Abstract] [Full Text]  
• Chew, C. S., Chen, X., Parente, J. A. Jr, Tarrer, S., Okamoto, C., Qin, H.-Y. (2003). Lasp-1 binds to non-muscle F-actin in vitro and is localized within multiple sites of dynamic actin assembly in vivo. J. Cell Sci. 115: 4787-4799 [Abstract] [Full Text]  
• Rogat, A. D., Miller, K. G. (2003). A role for myosin VI in actin dynamics at sites of membrane remodeling during Drosophila spermatogenesis. J. Cell Sci. 115: 4855-4865 [Abstract] [Full Text]  
• Krueger, E. W., Orth, J. D., Cao, H., McNiven, M. A. (2003). A Dynamin-Cortactin-Arp2/3 Complex Mediates Actin Reorganization in Growth Factor-stimulated Cells. Mol. Biol. Cell 14: 1085-1096 [Abstract] [Full Text]  
• Humphries, C. L., Balcer, H. I., D'Agostino, J. L., Winsor, B., Drubin, D. G., Barnes, G., Andrews, B. J., Goode, B. L. (2002). Direct regulation of Arp2/3 complex activity and function by the actin binding protein coronin. JCB 159: 993-1004 [Abstract] [Full Text]  
• Di Ciano, C., Nie, Z., Szaszi, K., Lewis, A., Uruno, T., Zhan, X., Rotstein, O. D., Mak, A., Kapus, A. (2002). Osmotic stress-induced remodeling of the cortical cytoskeleton. Am. J. Physiol. Cell Physiol. 283: C850-C865 [Abstract] [Full Text]  

Home | Help | Feedback | Subscriptions | Archive | Search | Table of Contents