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© The Rockefeller University Press, 0021-9525/2001/11/501 $5.00
The Journal of Cell Biology, Volume 155, Number 4, November 12, 2001 501-504

Tethering and tickling

Selin Somersan and Nina Bhardwaj

The Laboratory of Molecular Neuro-Oncology, The Rockefeller University, New York, NY, 10021

Address correspondence to Nina Bhardwaj, The Laboratory of Molecular Neuro-Oncology, The Rockefeller University, Room 41, Box #176, 1230 York Ave., New York, NY 10021. Tel.: (212) 327-8332. Fax: (212) 327-7232. E-mail bhardwn{at}mail.rockefeller.edu

Several receptors are implicated in apoptotic cell (AC) uptake by phagocytic cells; however, their relative dominance in mammalian systems remains to be established. New studies shed light on the role of the phosphatidyl serine (PS) receptor (PSR). Ligation of PSR by PS on AC surfaces is considered essential for signaling uptake of ACs that are tethered to phagocytes via other receptors.

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