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Published online 26 March 2002. doi:10.1083/jcb.200203037
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© The Rockefeller University Press, 0021-9525/2002/4/15 $5.00
The Journal of Cell Biology, Volume 157, Number 1, April 1, 2002 15-18


Feature

Is transdifferentiation in trouble?



William A. Wells

wellsw{at}rockefeller.edu


Abstract

Spectacular examples of transdifferentiation—such as brain cells turning to blood and blood to brain—have given way to sneaking suspicions about artifacts in culture, fusion, and clonality. Could cell fates be relatively fixed after all?


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