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Can telomerase be put in its place?

Program in Cell Dynamics and Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605

Address correspondence to Thoru Pederson, Program in Cell Dynamics and Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605. Tel.: (508) 856-8667. Fax: (508) 856-8668. email: thoru.pederson{at}umassmed.edu

The Cajal body is an intriguing nuclear structure present in a great variety of plant, animal, and some fungal cells. Recent work on the ribonucleoprotein enzyme telomerase has indicated an unanticipated degree of intranuclear dynamics of both its RNA and protein subunits. In this issue, Jady et al. place the Cajal body on the intranuclear traffic route of telomerase RNA (Jady et al., 2004).

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