Home | Help | Feedback | Subscriptions | Archive | Search | Table of Contents

This Article Full Text Full Text (PDF, 430K) PPT slides of all figures Alert me when this article is cited Citation Map Services Email this article Similar articles in this journal Similar articles in PubMed Alert me to new content in the JCB Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Putney, J. W. Search for Related Content PubMed PubMed Citation Articles by Putney, J. W., Jr. Related Collections Related Article Social Bookmarking                            What's this?

Capacitative calcium entry

James W. Putney, Jr.

Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, National Institutes of Health Department of Health and Human Services, Research Triangle Park, NC 27709

Correspondence to James W. Putney, Jr: putney{at}niehs.nih.gov

Abstract

A long-standing mystery in the cell biology of calcium channel regulation is the nature of the signal linking intracellular calcium stores to plasma membrane capacitative calcium entry channels. An RNAi-based screen of selected Drosophila genes has revealed that a calcium-binding protein, stromal interaction molecule (STIM), plays an essential role in the activation of these channels and may be the long sought sensor of calcium store content.

Abbreviations used in this paper: CIF, calcium influx factor; IP₃, inositol 1,4,5-trisphosphate; SAM, sterile motif; STIM, stromal interaction molecule.

CiteULike    Complore    Connotea    Del.icio.us    Digg    Facebook    Reddit    Technorati    Twitter    What's this?

Related Article

STIM1, an essential and conserved component of store-operated Ca²⁺ channel function

Jack Roos, Paul J. DiGregorio, Andriy V. Yeromin, Kari Ohlsen, Maria Lioudyno, Shenyuan Zhang, Olga Safrina, J. Ashot Kozak, Steven L. Wagner, Michael D. Cahalan, Gönül Veliçelebi, and Kenneth A. Stauderman
J. Cell Biol. 2005 169: 435-445. [Abstract] [Full Text] [PDF]

This article has been cited by other articles:

• Zhang, L., Li, L., Liu, H., Borowitz, J. L., Isom, G. E. (2009). BNIP3 mediates cell death by different pathways following localization to endoplasmic reticulum and mitochondrion. FASEB J. 23: 3405-3414 [Abstract] [Full Text]  
• Monastyrskaya, K., Babiychuk, E. B., Hostettler, A., Wood, P., Grewal, T., Draeger, A. (2009). Plasma Membrane-associated Annexin A6 Reduces Ca2+ Entry by Stabilizing the Cortical Actin Cytoskeleton. J. Biol. Chem. 284: 17227-17242 [Abstract] [Full Text]  
• Goyal, R., Creel, K. D., Chavis, E., Smith, G. D., Longo, L. D., Wilson, S. M. (2008). Maturation of intracellular calcium homeostasis in sheep pulmonary arterial smooth muscle cells. Am. J. Physiol. Lung Cell. Mol. Physiol. 295: L905-L914 [Abstract] [Full Text]  
• Jardin, I., Lopez, J. J., Salido, G. M., Rosado, J. A. (2008). Orai1 Mediates the Interaction between STIM1 and hTRPC1 and Regulates the Mode of Activation of hTRPC1-forming Ca2+ Channels. J. Biol. Chem. 283: 25296-25304 [Abstract] [Full Text]  
• Da Silva, N., Herron, C. E., Stevens, K., Jollimore, C. A. B., Barnes, S., Kelly, M. E. M. (2008). Metabotropic Receptor-Activated Calcium Increases and Store-Operated Calcium Influx in Mouse Muller Cells. IOVS 49: 3065-3073 [Abstract] [Full Text]  
• Sieck, G. C., White, T. A., Thompson, M. A., Pabelick, C. M., Wylam, M. E., Prakash, Y. S. (2008). Regulation of store-operated Ca2+ entry by CD38 in human airway smooth muscle. Am. J. Physiol. Lung Cell. Mol. Physiol. 294: L378-L385 [Abstract] [Full Text]  
• Prakash, Y. S., Thompson, M. A., Vaa, B., Matabdin, I., Peterson, T. E., He, T., Pabelick, C. M. (2007). Caveolins and intracellular calcium regulation in human airway smooth muscle. Am. J. Physiol. Lung Cell. Mol. Physiol. 293: L1118-L1126 [Abstract] [Full Text]  
• Suzuki, F., Morishima, S., Tanaka, T., Muramatsu, I. (2007). Snapin, a New Regulator of Receptor Signaling, Augments {alpha}1A-Adrenoceptor-operated Calcium Influx through TRPC6. J. Biol. Chem. 282: 29563-29573 [Abstract] [Full Text]  
• Hong, M., Ross, W. N. (2007). Priming of intracellular calcium stores in rat CA1 pyramidal neurons. J. Physiol. 584: 75-87 [Abstract] [Full Text]  
• Hirota, S., Helli, P., Janssen, L. J. (2007). Ionic mechanisms and Ca2+ handling in airway smooth muscle. Eur Respir J 30: 114-133 [Abstract] [Full Text]  
• Hu, B. S., Landeen, L. K., Aroonsakool, N., Giles, W. R. (2007). An analysis of the effects of stretch on IGF-I secretion from rat ventricular fibroblasts. Am. J. Physiol. Heart Circ. Physiol. 293: H677-H683 [Abstract] [Full Text]  
• Mignen, O., Thompson, J. L., Shuttleworth, T. J. (2007). STIM1 regulates Ca2+ entry via arachidonate-regulated Ca2+-selective (ARC) channels without store depletion or translocation to the plasma membrane. J. Physiol. 579: 703-715 [Abstract] [Full Text]  
• Nilius, B., Owsianik, G., Voets, T., Peters, J. A. (2007). Transient Receptor Potential Cation Channels in Disease. Physiol. Rev. 87: 165-217 [Abstract] [Full Text]  
• Peters, S. C., Piper, H. M. (2007). Reoxygenation-induced Ca2+ rise is mediated via Ca2+ influx and Ca2+ release from the endoplasmic reticulum in cardiac endothelial cells. Cardiovasc Res 73: 164-171 [Abstract] [Full Text]  
• Stathopulos, P. B., Li, G.-Y., Plevin, M. J., Ames, J. B., Ikura, M. (2006). Stored Ca2+ Depletion-induced Oligomerization of Stromal Interaction Molecule 1 (STIM1) via the EF-SAM Region: AN INITIATION MECHANISM FOR CAPACITIVE Ca2+ ENTRY. J. Biol. Chem. 281: 35855-35862 [Abstract] [Full Text]  
• Baba, Y., Hayashi, K., Fujii, Y., Mizushima, A., Watarai, H., Wakamori, M., Numaga, T., Mori, Y., Iino, M., Hikida, M., Kurosaki, T. (2006). Coupling of STIM1 to store-operated Ca2+ entry through its constitutive and inducible movement in the endoplasmic reticulum. Proc. Natl. Acad. Sci. USA 103: 16704-16709 [Abstract] [Full Text]  
• Lopez, JoseJ., Salido, G. M., Pariente, J. A., Rosado, J. A. (2006). Interaction of STIM1 with Endogenously Expressed Human Canonical TRP1 upon Depletion of Intracellular Ca2+ Stores. J. Biol. Chem. 281: 28254-28264 [Abstract] [Full Text]  
• Wang, J., Wang, N., Xie, J., Walton, S. C., McKown, R. L., Raab, R. W., Ma, P., Beck, S. L., Coffman, G. L., Hussaini, I. M., Laurie, G. W. (2006). Restricted epithelial proliferation by lacritin via PKC{alpha}-dependent NFAT and mTOR pathways. JCB 174: 689-700 [Abstract] [Full Text]  
• Mauban, J. R. H., Wilkinson, K., Schach, C., Yuan, J. X.-J. (2006). Histamine-mediated increases in cytosolic [Ca2+] involve different mechanisms in human pulmonary artery smooth muscle and endothelial cells. Am. J. Physiol. Cell Physiol. 290: C325-C336 [Abstract] [Full Text]  

Home | Help | Feedback | Subscriptions | Archive | Search | Table of Contents