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Published online 16 October 2006. doi:10.1083/jcb.200608058
The Rockefeller University Press, 0021-9525 $8.00
JCB, Volume 175, Number 2, 199-200
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Darkness descends with two Rabs



Michael S. Marks

University of Pennsylvania, Philadelphia, PA 19104

Correspondence to Michael S. Marks: marksm{at}mail.med.upenn.edu


Abstract

Over 60 distinct Rab GTPases regulate specific vesicular transport steps in the mammalian central vacuolar system. Wasmeier et al. (this issue, p. 271) reveal a redundant role for two tissue-specific Rab proteins in regulating transport to a tissue-specific lysosome-related organelle, the melanosome.


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