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Published online
doi:10.1083/jcb.200711098
The Journal of Cell Biology, Vol. 179, No. 6, 1093-1094
The Rockefeller University Press, 0021-9525 $30.00
© Carmo-Fonseca
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How genes find their way inside the cell nucleus



Maria Carmo-Fonseca

Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, 1649-028 Lisboa, Portugal

Correspondence to Maria Carmo-Fonseca: carmo.fonseca{at}fm.ul.pt

Recent progress in live cell imaging suggests a role for nuclear actin in chromatin movement. In this issue, for the first time, a gene locus moving toward a subnuclear compartment was tracked. Motion of the locus is actin dependent, raising the question of whether chromatin movements are random or directed.


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