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Published online
doi:10.1083/jcb.200802174
The Journal of Cell Biology, Vol. 180, No. 6, 1059-1060
The Rockefeller University Press, 0021-9525 $30.00
© Kaksonen
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Taking apart the endocytic machinery



Marko Kaksonen

Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, 69117 Heidelberg, Germany

Correspondence to Marko Kaksonen: kaksonen{at}embl.de

The formation of clathrin-coated endocytic vesicles is driven by a complex and highly dynamic molecular machinery. In this issue, Idrissi et al. (Idrissi, F.-Z., H. Grötsch, I.M. Fernández-Golbano, C. Presciatto-Baschong, H. Riezman, and M.-I. Geli. 2008. J. Cell Biol. 180:1219–1232) reveal some of the secrets of this machinery by analyzing the localizations of nine endocytic proteins during vesicle budding in yeast using quantitative immunoelectron microscopy.


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Related Article

Distinct acto/myosin-I structures associate with endocytic profiles at the plasma membrane
Fatima-Zahra Idrissi, Helga Grötsch, Isabel M. Fernández-Golbano, Cristina Presciatto-Baschong, Howard Riezman, and María-Isabel Geli
J. Cell Biol. 2008 180: 1219-1232. [Abstract] [Full Text] [PDF]





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