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Published online
doi:10.1083/jcb.200909134
The Journal of Cell Biology, Vol. 187, No. 2, 157-159
The Rockefeller University Press, 0021-9525 $30.00
© Kellner et al.
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Keratins and protein synthesis: the plot thickens



Juliane C. Kellner and Pierre A. Coulombe

Department of Biochemistry and Molecular Biology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 20723

Correspondence to Pierre A. Coulombe: coulombe{at}jhsph.edu

In addition to protecting epithelial cells from mechanical stress, keratins regulate cytoarchitecture, cell growth, proliferation, apoptosis, and organelle transport. In this issue, Vijayaraj et al. (2009. J. Cell Biol. doi:10.1083/jcb.200906094) expand our understanding of how keratin proteins participate in the regulation of protein synthesis through their analysis of mice lacking the entire type II keratin gene cluster.


© 2009 Kellner and Coulombe
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J. Cell Biol. 2009 187: 175-184. [Abstract] [Full Text] [PDF]





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