ARTICLE

THE EFFECT OF THYMIDINE ON THE DURATION OF G₁ IN CHINESE HAMSTER CELLS

¹ From the Biomedical Research Group, Los Alamos Scientific Laboratory, University of California, Los Alamos, New Mexico 87544

The generation time of a Chinese hamster cell line was varied by the use of different lots of sera in the culture media. Analysis of the division waves following thymidine synchronization showed that lengthening of the generation time was a result of an increase in duration of the G₁ phase and that thymidine treatment reduced the duration of G₁ back to its minimum value.

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