Rapid flow cytofluorometric analysis of mammalian cell cycle by propidium iodide staining

doi:10.1083/jcb.66.1.188

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Rapid flow cytofluorometric analysis of mammalian cell cycle by propidium iodide staining

A Krishan

A rapid method for the flow microfluorometric determination of the DNA content per cell is described. Incubation of cells in a hypotonic solution of propidium iodide results in disruption of the cell membrane and rapid staining of nuclear chromatin. DNA distribution histograms generated from cells stained by this method are identical to those generated after fixation and RNase digestion. In contrast to some earlier described methods, the present technique is rapid (5 min of processing), requires a minimal amount of material, and avoids formation of cell clumps.
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Krishan, A., Dandekar, P. D. (2005). DAPI Fluorescence in Nuclei Isolated from Tumors. J. Histochem. Cytochem. 53: 1033-1036 [Abstract] [Full Text]
Ueda, Y., Kondo, M., Kelsoe, G. (2005). Inflammation and the reciprocal production of granulocytes and lymphocytes in bone marrow. JEM 201: 1771-1780 [Abstract] [Full Text]
Krankel, N., Adams, V., Linke, A., Gielen, S., Erbs, S., Lenk, K., Schuler, G., Hambrecht, R. (2005). Hyperglycemia Reduces Survival and Impairs Function of Circulating Blood-Derived Progenitor Cells. Arterioscler. Thromb. Vasc. Bio. 25: 698-703 [Abstract] [Full Text]
John, G. B., Shang, Y., Li, L., Renken, C., Mannella, C. A., Selker, J. M.L., Rangell, L., Bennett, M. J., Zha, J. (2005). The Mitochondrial Inner Membrane Protein Mitofilin Controls Cristae Morphology. Mol. Biol. Cell 16: 1543-1554 [Abstract] [Full Text]
Ghosh, R., Nadiminty, N., Fitzpatrick, J. E., Alworth, W. L., Slaga, T. J., Kumar, A. P. (2005). Eugenol Causes Melanoma Growth Suppression through Inhibition of E2F1 Transcriptional Activity. J. Biol. Chem. 280: 5812-5819 [Abstract] [Full Text]
Goulet, A.-C., Chigbrow, M., Frisk, P., Nelson, M. A. (2005). Selenomethionine induces sustained ERK phosphorylation leading to cell-cycle arrest in human colon cancer cells. Carcinogenesis 26: 109-117 [Abstract] [Full Text]
Mooberry, S. L., Randall-Hlubek, D. A., Leal, R. M., Hegde, S. G., Hubbard, R. D., Zhang, L., Wender, P. A. (2004). From the Cover: Microtubule-stabilizing agents based on designed laulimalide analogues. Proc. Natl. Acad. Sci. USA 101: 8803-8808 [Abstract] [Full Text]
Zheng, B., Georgakis, G. V., Li, Y., Bharti, A., McConkey, D., Aggarwal, B. B., Younes, A. (2004). Induction of Cell Cycle Arrest and Apoptosis by the Proteasome Inhibitor PS-341 in Hodgkin Disease Cell Lines Is Independent of Inhibitor of Nuclear Factor-{kappa}B Mutations or Activation of the CD30, CD40, and RANK Receptors. Clin. Cancer Res. 10: 3207-3215 [Abstract] [Full Text]
Hernandez-Hansen, V., Mackay, G. A., Lowell, C. A., Wilson, B. S., Oliver, J. M. (2004). The Src kinase Lyn is a negative regulator of mast cell proliferation. J. Leukoc. Biol. 75: 143-151 [Abstract] [Full Text]
Pierantoni, G. M., Battista, S., Pentimalli, F., Fedele, M., Visone, R., Federico, A., Santoro, M., Viglietto, G., Fusco, A. (2003). A truncated HMGA1 gene induces proliferation of the 3T3-L1 pre-adipocytic cells: a model of human lipomas. Carcinogenesis 24: 1861-1869 [Abstract] [Full Text]
Do, Y., Rafi-Janajreh, A. Q., Mckallip, R. J., Nagarkatti, P. S., Nagarkatti, M. (2003). Combined deficiency in CD44 and Fas leads to exacerbation of lymphoproliferative and autoimmune disease. Int Immunol 15: 1327-1340 [Abstract] [Full Text]
Faiola, B., Bauer, A. K., Fuller, E. S., Wong, V. A., Pluta, L. J., Abernethy, D. J., Mangum, J. B., Everitt, J. I., Recio, L. (2003). Variations in Prkdc and Susceptibility to Benzene-Induced Toxicity in Mice. Toxicol Sci 75: 321-332 [Abstract] [Full Text]
Nakanishi, T., Karp, J. E., Tan, M., Doyle, L. A., Peters, T., Yang, W., Wei, D., Ross, D. D. (2003). Quantitative Analysis of Breast Cancer Resistance Protein and Cellular Resistance to Flavopiridol in Acute Leukemia Patients. Clin. Cancer Res. 9: 3320-3328 [Abstract] [Full Text]
Chang, M., Nakagawa, P. A., Williams, S. A., Schwartz, M. R., Imfeld, K. L., Buzby, J. S., Nugent, D. J. (2003). Immune thrombocytopenic purpura (ITP) plasma and purified ITP monoclonal autoantibodies inhibit megakaryocytopoiesis in vitro. Blood 102: 887-895 [Abstract] [Full Text]
Zheng, B., Fiumara, P., Li, Y. V., Georgakis, G., Snell, V., Younes, M., Vauthey, J. N., Carbone, A., Younes, A. (2003). MEK/ERK pathway is aberrantly active in Hodgkin disease: a signaling pathway shared by CD30, CD40, and RANK that regulates cell proliferation and survival. Blood 102: 1019-1027 [Abstract] [Full Text]
Tinley, T. L., Randall-Hlubek, D. A., Leal, R. M., Jackson, E. M., Cessac, J. W., Quada, J. C. Jr., Hemscheidt, T. K., Mooberry, S. L. (2003). Taccalonolides E and A: Plant-derived Steroids with Microtubule-stabilizing Activity. Cancer Res. 63: 3211-3220 [Abstract] [Full Text]
Agate, R. J., Grisham, W., Wade, J., Mann, S., Wingfield, J., Schanen, C., Palotie, A., Arnold, A. P. (2003). Neural, not gonadal, origin of brain sex differences in a gynandromorphic finch. Proc. Natl. Acad. Sci. USA 100: 4873-4878 [Abstract] [Full Text]
Ni, J., Hembrador, E., Di Bisceglie, A. M., Jacobson, I. M., Talal, A. H., Butera, D., Rice, C. M., Chambers, T. J., Dustin, L. B. (2003). Accumulation of B Lymphocytes with a Naive, Resting Phenotype in a Subset of Hepatitis C Patients. J. Immunol. 170: 3429-3439 [Abstract] [Full Text]
Roy, S., Khanna, S., Bickerstaff, A. A., Subramanian, S. V., Atalay, M., Bierl, M., Pendyala, S., Levy, D., Sharma, N., Venojarvi, M., Strauch, A., Orosz, C. G., Sen, C. K. (2003). Oxygen Sensing by Primary Cardiac Fibroblasts: A Key Role of p21Waf1/Cip1/Sdi1. Circ. Res. 92: 264-271 [Abstract] [Full Text]
Kumar, A. P., Garcia, G. E., Orsborn, J., Levin, V. A., Slaga, T. J. (2003). 2-Methoxyestradiol interferes with NF{kappa}B transcriptional activity in primitive neuroectodermal brain tumors: implications for management. Carcinogenesis 24: 209-216 [Abstract] [Full Text]
Petit, T., Bearss, D. J., Troyer, D. A., Munoz, R. M., Windle, J. J. (2003). p53-independent Response to Cisplatin and Oxaliplatin in MMTV-ras Mouse Salivary Tumors. Molecular Cancer Therapeutics 2: 165-171 [Abstract] [Full Text]
Jiang, W., Zhu, Z., Bhatia, N., Agarwal, R., Thompson, H. J. (2002). Mechanisms of Energy Restriction: Effects of Corticosterone on Cell Growth, Cell Cycle Machinery, and Apoptosis. Cancer Res. 62: 5280-5287 [Abstract] [Full Text]
Gerhauser, C., Alt, A., Heiss, E., Gamal-Eldeen, A., Klimo, K., Knauft, J., Neumann, I., Scherf, H.-R., Frank, N., Bartsch, H., Becker, H. (2002). Cancer Chemopreventive Activity of Xanthohumol, a Natural Product Derived from Hop. Molecular Cancer Therapeutics 1: 959-969 [Abstract] [Full Text]
van Olphen, A. L., Mittal, S. K. (2002). Development and Characterization of Bovine x Human Hybrid Cell Lines That Efficiently Support the Replication of both Wild-Type Bovine and Human Adenoviruses and Those with E1 Deleted. J. Virol. 76: 5882-5892 [Abstract] [Full Text]
Wan, Y., Nordeen, S. K. (2002). Overlapping but Distinct Gene Regulation Profiles by Glucocorticoids and Progestins in Human Breast Cancer Cells. Mol. Endocrinol. 16: 1204-1214 [Abstract] [Full Text]
Bearss, D. J., Lee, R. J., Troyer, D. A., Pestell, R. G., Windle, J. J. (2002). Differential Effects of p21WAF1/CIP1 Deficiency on MMTV-ras and MMTV-myc Mammary Tumor Properties. Cancer Res. 62: 2077-2084 [Abstract] [Full Text]
Jackson, M. W., Roberts, J. S., Heckford, S. E., Ricciardelli, C., Stahl, J., Horsfall, D. J., Tilley, W. D. (2002). A Potential Autocrine Role for Vascular Endothelial Growth Factor in Prostate Cancer. Cancer Res. 62: 854-859 [Abstract] [Full Text]
Zhu, Z., Jiang, W., Ganther, H. E., Thompson, H. J. (2002). Mechanisms of Cell Cycle Arrest by Methylseleninic Acid. Cancer Res. 62: 156-164 [Abstract] [Full Text]
Fouty, B. W., Grimison, B., Fagan, K. A., Le Cras, T. D., Harral, J. W., Hoedt-Miller, M., Sclafani, R. A., Rodman, D. M. (2001). p27Kip1 Is Important in Modulating Pulmonary Artery Smooth Muscle Cell Proliferation. Am. J. Respir. Cell Mol. Bio. 25: 652-658 [Abstract] [Full Text]
Kramer, D. L., Chang, B.-D., Chen, Y., Diegelman, P., Alm, K., Black, A. R., Roninson, I. B., Porter, C. W. (2001). Polyamine Depletion in Human Melanoma Cells Leads to G1 Arrest Associated with Induction of p21WAF1/CIP1/SDI1, Changes in the Expression of p21-regulated Genes, and a Senescence-like Phenotype. Cancer Res. 61: 7754-7762 [Abstract] [Full Text]
Rooney, R. J. (2001). Cell Cycle Attenuation by p120E4F Is Accompanied by Increased Mitotic Dysfunction. Cell Growth Differ. 12: 505-516 [Abstract] [Full Text]
Zhu, X., Kwon, C.-H., Schlosshauer, P. W., Ellenson, L. H., Baker, S. J. (2001). PTEN Induces G1 Cell Cycle Arrest and Decreases Cyclin D3 Levels in Endometrial Carcinoma Cells. Cancer Res. 61: 4569-4575 [Abstract] [Full Text]
Fedele, M., Pierantoni, G. M., Berlingieri, M. T., Battista, S., Baldassarre, G., Munshi, N., Dentice, M., Thanos, D., Santoro, M., Viglietto, G., Fusco, A. (2001). Overexpression of Proteins HMGA1 Induces Cell Cycle Deregulation and Apoptosis in Normal Rat Thyroid Cells. Cancer Res. 61: 4583-4590 [Abstract] [Full Text]
Geroni, C., Ripamonti, M., Arrigoni, C., Fiorentini, F., Capolongo, L., Moneta, D., Marchini, S., Torre, P. D., Albanese, C., Lamparelli, M. G., Ciomei, M., Rossi, R., Caruso, M. (2001). Pharmacological and Toxicological Aspects of 4-Demethoxy-3'-deamino-3'-aziridinyl-4'-methylsulphonyl-daunorubicin (PNU-159548): A Novel Antineoplastic Agent. Cancer Res. 61: 1983-1990 [Abstract] [Full Text]
Srivannaboon, K., Shanafelt, A. B., Todisco, E., Forte, C. P., Behm, F. G., Raimondi, S. C., Pui, C.-H., Campana, D. (2001). Interleukin-4 variant (BAY 36-1677) selectively induces apoptosis in acute lymphoblastic leukemia cells. Blood 97: 752-758 [Abstract] [Full Text]
Poggioli, G. J., Keefer, C., Connolly, J. L., Dermody, T. S., Tyler, K. L. (2000). Reovirus-Induced G2/M Cell Cycle Arrest Requires sigma 1s and Occurs in the Absence of Apoptosis. J. Virol. 74: 9562-9570 [Abstract] [Full Text]
Aston, N S, Watt, N, Morton, I E, Tanner, M S, Evans, G S (2000). Copper toxicity affects proliferation and viability of human hepatoma cells (HepG2 line). Hum Exp Toxicol 19: 367-376 [Abstract]
Takaba, K., Saeki, K., Suzuki, K., Wanibuchi, H., Fukushima, S. (2000). Significant overexpression of metallothionein and cyclin D1 and apoptosis in the early process of rat urinary bladder carcinogenesis induced by treatment with N-butyl-N-(4-hydroxybutyl)nitrosamine or sodium L-ascorbate. Carcinogenesis 21: 691-700 [Abstract] [Full Text]
Chan, J. R., Boger, R. H., Bode-Boger, S. M., Tangphao, O., Tsao, P. S., Blaschke, T. F., Cooke, J. P. (2000). Asymmetric Dimethylarginine Increases Mononuclear Cell Adhesiveness in Hypercholesterolemic Humans. Arterioscler. Thromb. Vasc. Bio. 20: 1040-1046 [Abstract] [Full Text]
Todisco, E., Suzuki, T., Srivannaboon, K., Coustan-Smith, E., Raimondi, S. C., Behm, F. G., Kitanaka, A., Campana, D. (2000). CD38 ligation inhibits normal and leukemic myelopoiesis. Blood 95: 535-542 [Abstract] [Full Text]
Harvey, K. J., Lukovic, D., Ucker, D. S. (2000). Caspase-Dependent Cdk Activity Is a Requisite Effector of Apoptotic Death Events. JCB 148: 59-72 [Abstract] [Full Text]
Soriano, A. F., Helfrich, B., Chan, D. C., Heasley, L. E., Bunn, P. A. Jr., Chou, T.-C. (1999). Synergistic Effects of New Chemopreventive Agents and Conventional Cytotoxic Agents against Human Lung Cancer Cell Lines. Cancer Res. 59: 6178-6184 [Abstract] [Full Text]
COPANI, A., CONDORELLI, F., CARUSO, A., VANCHERI, C., SALA, A., GIUFFRIDA STELLA, A. M., CANONICO, P. L., NICOLETTI, F., SORTINO, M. A. (1999). Mitotic signaling by {beta}-amyloid causes neuronal death. FASEB J. 13: 2225-2234 [Abstract] [Full Text]
Epsztejn, S., Glickstein, H., Picard, V., Slotki, I. N., Breuer, W., Beaumont, C., Cabantchik, Z. I. (1999). H-Ferritin Subunit Overexpression in Erythroid Cells Reduces the Oxidative Stress Response and Induces Multidrug Resistance Properties. Blood 94: 3593-3603 [Abstract] [Full Text]
Nguyen, D. M., Chen, A., Mixon, A., Schrump, D. S., Roth, S. J. A. (1999). SEQUENCE-DEPENDENT ENHANCEMENT OF PACLITAXEL TOXICITY IN NON-SMALL CELL LUNG CANCER BY 17-ALLYLAMINO 17-DEMETHOXYGELDANAMYCIN. J. Thorac. Cardiovasc. Surg. 118: 908-915 [Abstract] [Full Text]
Schul, W., van der Kraan, I., Matera, A. G., van Driel, R., de Jong, L. (1999). Nuclear Domains Enriched in RNA 3'-processing Factors Associate with Coiled Bodies and Histone Genes in a Cell Cycle-dependent Manner. Mol. Biol. Cell 10: 3815-3824 [Abstract] [Full Text]
Ruf, I. K., Sample, J. (1999). Repression of Epstein-Barr Virus EBNA-1 Gene Transcription by pRb during Restricted Latency. J. Virol. 73: 7943-7951 [Abstract] [Full Text]
Mori, C., Allen, J. W., Dix, D. J., Nakamura, N., Fujioka, M., Toshimori, K., Eddy, E. M. (1999). Completion of Meiosis Is Not Always Required for Acrosome Formation in HSP70-2 Null Mice. Biol. Reprod. 61: 813-822 [Abstract] [Full Text]
Maurer, B. J., Metelitsa, L. S., Seeger, R. C., Cabot, M. C., Reynolds, C. P. (1999). Increase of Ceramide and Induction of Mixed Apoptosis/Necrosis by N-(4-Hydroxyphenyl)- retinamide in Neuroblastoma Cell Lines. JNCI J Natl Cancer Inst 91: 1138-1146 [Abstract] [Full Text]
Fernandes, E. R., Rooney, R. J. (1999). Suppression of E1A-Mediated Transformation by the p50E4F Transcription Factor. Mol. Cell. Biol. 19: 4739-4749 [Abstract] [Full Text]
Feng, Y.-Q., Alami, R., Bouhassira, E. E. (1999). Enhancer-Dependent Transcriptional Oscillations in Mouse Erythroleukemia Cells. Mol. Cell. Biol. 19: 4907-4917 [Abstract] [Full Text]
Vyas, P., Ault, K., Jackson, C. W., Orkin, S. H., Shivdasani, R. A. (1999). Consequences of GATA-1 Deficiency in Megakaryocytes and Platelets. Blood 93: 2867-2875 [Abstract] [Full Text]
Segovia, J. C., Gallego, J. M., Bueren, J. A., Almendral, J. M. (1999). Severe Leukopenia and Dysregulated Erythropoiesis in SCID Mice Persistently Infected with the Parvovirus Minute Virus of Mice. J. Virol. 73: 1774-1784 [Abstract] [Full Text]
Kramer, D. L., Vujcic, S., Diegelman, P., Alderfer, J., Miller, J. T., Black, J. D., Bergeron, R. J., Porter, C. W. (1999). Polyamine Analogue Induction of the p53-p21WAF1/CIP1-Rb Pathway and G1 Arrest in Human Melanoma Cells. Cancer Res. 59: 1278-1286 [Abstract] [Full Text]
Persons, D. A., Allay, J. A., Allay, E. R., Ashmun, R. A., Orlic, D., Jane, S. M., Cunningham, J. M., Nienhuis, A. W. (1999). Enforced Expression of the GATA-2 Transcription Factor Blocks Normal Hematopoiesis. Blood 93: 488-499 [Abstract] [Full Text]
Carr, J., Shearer, G. Jr. (1998). Genome Size, Complexity, and Ploidy of the Pathogenic Fungus Histoplasma capsulatum. J. Bacteriol. 180: 6697-6703 [Abstract] [Full Text]
Quadri, R. A., Arbogast, A., Phelouzat, M.-A., Boutet, S., Plastre, O., Proust, J. J. (1998). Age-Associated Decline in cdk1 Activity Delays Cell Cycle Progression of Human T Lymphocytes. J. Immunol. 161: 5203-5209 [Abstract] [Full Text]
Wu-Hsieh, B. A., Chen, W., Lee, H.-J. (1998). Nitric Oxide Synthase Expression in Macrophages of Histoplasma capsulatum-Infected Mice Is Associated with Splenocyte Apoptosis and Unresponsiveness. Infect. Immun. 66: 5520-5526 [Abstract] [Full Text]
Wiater, L. A., Dunn, K., Maxfield, F. R., Shuman, H. A. (1998). Early Events in Phagosome Establishment Are Required for Intracellular Survival of Legionella pneumophila. Infect. Immun. 66: 4450-4460 [Abstract] [Full Text]
Suzuki, N., Del Villar, K., Tamanoi, F. (1998). Farnesyltransferase inhibitors induce dramatic morphological changes of KNRK cells that are blocked by microtubule interfering agents. Proc. Natl. Acad. Sci. USA 95: 10499-10504 [Abstract] [Full Text]
Harvey, K. J., Blomquist, J. F., Ucker, D. S. (1998). Commitment and Effector Phases of the Physiological Cell Death Pathway Elucidated with Respect to Bcl-2, Caspase, and Cyclin-Dependent Kinase Activities. Mol. Cell. Biol. 18: 2912-2922 [Abstract] [Full Text]
Slack, J. L., Yu, M. (1998). Constitutive Expression of the Promyelocytic Leukemia-Associated Oncogene PML-RARalpha in TF1 Cells: Isoform-Specific and Retinoic Acid-Dependent Effects on Growth, bcl-2 Expression, and Apoptosis. Blood 91: 3347-3356 [Abstract] [Full Text]
Goossens, T., Klein, U., Kuppers, R. (1998). Frequent occurrence of deletions and duplications during somatic hypermutation: Implications for oncogene translocations and heavy chain disease. Proc. Natl. Acad. Sci. USA 95: 2463-2468 [Abstract] [Full Text]
Fernandes, E. R., Zhang, J. Y., Rooney, R. J. (1998). Adenovirus E1A-Regulated Transcription Factor p120E4F Inhibits Cell Growth and Induces the Stabilization of the cdk Inhibitor p21WAF1. Mol. Cell. Biol. 18: 459-467 [Abstract] [Full Text]