The Journal of Cell Biology, Vol 67, 901-904, Copyright © 1975 by The Rockefeller University Press
A feedback control of cell cycle parameters in Tetrahymena
F Jauker
Protein and RNA contents of individual cells were measured
cytophotometrically and related to the duration of individual generation
times. Constant amounts of RNA per cell at division, and generation
time-dependent protein contents, resulted in generation time- specific
RNA/protein ratios. Experimental reduction of these ratios by inhibition of
RNA synthesis stimulated premature macronuclear S phases.