A modified procedure for the isolation of a pore complex-lamina fraction from rat liver nuclei

doi:10.1083/jcb.70.3.581

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A modified procedure for the isolation of a pore complex-lamina fraction from rat liver nuclei

N Dwyer and G Blobel

A modified procedure for the isolation of a nuclear pore complex-lamina fraction from rat liver nuclei is described. Evidence is provided that the isolated lamina, a 150-A thick, proteinaceous structure, apposes the inner nuclear envelope membrane, connecting nuclear pore complexes and surrounding the entire nucleus.
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