Correction
for
Manning, J. Cell Biol. 167 (3) 399-403.
Published 20 December 2004. doi:10.1083/jcb200408161113004c
The Rockefeller University Press, 0021-9525 $8.00
JCB, Volume 167, Number 6, 1255-1255
Brendan D. Manning
Vol. 167, No. 3, November 8, 2004. Pages 399403.
During the production of this review, an error was introduced to the third sentence of the second paragraph: the second occurrence of "of serine" was mistakenly inserted and does not refer to the degradation and/or decrease in expression of IRS. The corrected sentence appears below.
A primary mechanism that has surfaced from these studies is the inhibition of IRS protein function through the phosphorylation of serine residues, degradation, and/or decrease in expression that disconnect the insulin receptor from PI3KAkt activation (for reviews see Saltiel and Kahn, 2001; White, 2002).

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