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Published 3 January 2005. doi:10.1083/jcb1681iti3
The Rockefeller University Press, 0021-9525 $8.00
JCB, Volume 168, Number 1, 9-9
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In This Issue

p107 Skps from S phase



Overexpressed p107 (open boxes) makes Skp2 unstable.

Pocket proteins find multiple routes to stop cell proliferation, according to results on page 55, from Rodier et al.The well-known antiproliferative route taken by pocket proteins, including pRb and p107, is through interaction with E2F. When bound to pRb, E2F cannot initiate the transcription of cell cycle progression genes, and cells thus linger in G1.



Nicole LeBrasseur

lebrasn{at}rockefeller.edu


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This Article
Right arrow Full Text (PDF, 2888K)
Right arrow PPT slides of all figures
Right arrow Alert me when this article is cited
Services
Right arrow Email this article
Right arrow Similar articles in this journal
Right arrow Alert me to new content in the JCB
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by LeBrasseur, N.
Right arrow Search for Related Content
PubMed
Right arrow Articles by LeBrasseur, N.
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