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Index of Online Supplemental Material for
J. Cell Biol. 10.1083/jcb.200310024
Nagano et al.

Figure S1 Regulation of CD44 cleavage by different signals.

Figure S2 Characterization of metalloproteinases responsible for ectodomain cleavage of CD44.

Figure S3 Ca2+ influx-induced cell detachment from an HA matrix is suppressed in ADAM10-/- MEFs.

Figure S4 Rac activation is induced by TPA treatment and regulates membrane ruffling in U251MG cells.

Figure S5 Proposed model for regulation of ADAM10- and ADAM17-mediated CD44 ectodomain cleavages triggered by the distinct signaling pathways.





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