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Index of Online Supplemental Material for
J. Cell Biol. 10.1083/jcb.200406063
Gupton et al.
• Figure S1 Stereo pairs showing a portion of the leading edge of whole control and skTM-injected cell from the same cell cluster.
• Figure S2 Mena, VASP, and mDia2 localization are similar in control and skTM-injected cells.
• Figure S3 High levels of skTM does not alter filamin and cortactin distribution.
• Video 1 (7.9 MB) Cells containing skTM exhibit only one region of F-actin kinematic behavior at their leading edges.
• Video 2 (1.4 MB) High levels of skTM inhibit the kinetic signature of the lamellipodium.
• Video 3 (1.3 MB) High levels of skTM induce multiple filopodial protrusions from the cell edge.
• Video 4 (4.9 MB) High levels of skTM induce changes in distribution and dynamics of paxillin-containing substrate adhesions.
• Video 5 (8.2 MB) Cells with inhibited TM exhibit decreased lamellipodial protrusion persistence.
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