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Index of Online Supplemental Material for
J. Cell Biol. 10.1083/jcb.200503152
Pankov et al.
• Figure S1 Directionally persistent migration of mutant integrin cells and suppression by expression of active Rac.
• Figure S2 Effects of Rac1 siRNA knockdown or inhibition of PI 3-kinase on immunoblotted signaling molecules of primary human fibroblasts.
• Figure S3 Effects on cell migration of Rac1 knockdown by Rac1 siRNA duplexes or Rac1 overexpression.
• Figure S4 Lack of effects of Rac1 knockdown on integrins and morphology of cells with an integrin mutation or Rac1 knockdown.
• Figure S5 Analysis of cell migration in 2D and 3D environments by time-lapse recording.
• Video 1 (4.2 MB) Time-lapse phase-contrast movie of primary human fibroblasts migrating.
• Video 2 (3.8 MB) Time-lapse phase-contrast movie of primary human fibroblasts migrating.
• Video 3 (9.1 MB) Time-lapse phase-contrast movie of primary human fibroblasts migrating.
• Video 4 (3.6 MB) Time-lapse phase-contrast movie of human MCF-10A breast epithelial cells migrating.
• Video 5 (3.5 MB) Time-lapse phase-contrast movie of human MCF-10A breast epithelial cells migrating.
• Video 6 (4.2 MB) Time-lapse phase-contrast movie of malignant human U87-MG glioblastoma cells migrating.
• Video 7 (3.0 MB) Time-lapse phase-contrast movie of malignant human U87-MG glioblastoma cells migrating.
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