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Index of Online Supplemental Material for
J. Cell Biol. 10.1083/jcb.200506042
Cai et al.
• Figure S1 COOH terminus of syntabulin (600-663) is required for its association with mitochondria.
• Figure S2 Syntabulin (145-230) is required for binding to the kinesin cargo-binding domain (KHC-CBD).
• Figure S3 Syntabulin loss-of-function has no effect on the proper distribution of ER in neurons.
• Figure S4 Syntabulin loss-of-function does not disturb the morphology of Golgi in neurons.
• Video 1 (1.0 MB) The COOH-terminal tail of syntabulin is sufficient to target to mobile mitochondria along processes of living neurons.
• Video 2 (3.1 MB) Movement of DsRed-mito-labeled mitochondria in live hippocampal neurons expressing control siRNA.
• Video 3 (1.2 MB) Movement of DsRed-mito-labeled mitochondria in live hippocampal neurons expressing stb-siRNA.
• Video 4 (2.4 MB) Fast transport of DsRed-mito-labeled mitochondria in live hippocampal neurons expressing GFP control.
• Video 5 (2.0 MB) Expression of STB-KBD arrests anterograde movement of DsRed-mito-labeled mitochondria along neuronal processes.
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