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Index of Online Supplemental Material for
J. Cell Biol. 10.1083/jcb.200605187
King et al.
• Figure S1 Dot blots of prefibrillar and fibrillar Aβ42 and control proteins.
• Figure S2 Western blot of cell lysates from the scrambled siRNA- and tau siRNA-treated hippocampal neurons.
• Video 1 Microtubules disassemble in tau-expressing CV-1 cells exposed to prefibrillar Aβ42.
• Video 2 Microtubules disassemble in tau-expressing CV-1 cells exposed to prefibrillar Aβ40.
• Video 3 Tau is required for prefibrillar Aβ42 to induce microtubule disassembly.
• Video 4 Fibrillar Aβ42 does not induce microtubule disassembly in tau-expressing cells.
• Video 5 Prefibrillar Aβ42 does not induce microtubule disassembly in MAP2c-expressing cells.
• Video 6 Prefibrillar Aβ42 does not induce microtubule disassembly in cells expressing MAP2c chimera.
• Video 7 Prefibrillar Aβ42 induces microtubule disassembly in cells expressing tau chimera.
• Video 8 Prefibrillar Aβ42 induces microtubule disassembly in cells expressing the N-terminal tau arm.
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