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Index of Online Supplemental Material for
J. Cell Biol. 10.1083/jcb.200701120
Gadea et al.
• Figure S1 ROCK mediates p53-dependent regulation of the subcellular distribution of integrin β1 and ezrin in rounded migrating cells cultured in 3D Matrigel.
• Video 1 MEFs move using an elongated mode of motility in 3D matrix.
• Video 2 p53-/- MEFs move using a rounded mode of motility in 3D matrix.
• Video 3 Rounded blebbing movement is provoked by p53 deficiency in 3D matrix.
• Video 4 Elongated movement is driven by p53 activity in 3D matrix.
• Video 5 Spreading of a p53-/- MEF treated with Y27632.
• Video 6 ROCK-Δ1 promotes a rounded morphology.
• Video 7 Rounded movement is promoted by ROCK-Δ1 in 3D matrix.
• Video 8 p53 deficiency-driven rounded morphology depends on ROCK activity in 3D matrix.
• Video 9 p53 deficiency-driven rounded morphology depends on ROCK activity in 3D matrix.
• Video 10 p53 deficiency-driven rounded morphology is prevented by RhoE in 3D matrix.
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