|
|
|
|
|
|
|
||
| ||||||||||||||||||||||||||
Index of Online Supplemental Material for
J. Cell Biol. 10.1083/jcb.200706083
Ritchie et al.
• Figure S1 Validation of ATRX depletion in HeLa cells.
• Figure S2 ATRX depletion prolongs mitotic duration.
• Figure S3 HP1α and HP1β immunocytochemistry in ATRX-depleted cells.
• Figure S4 Abnormal mitotic spindle morphology in ATRX-depleted cells.
• Video 1 Time-lapse video microscopy of an ATRX-depleted HG-shATRX1 cell arrested during mitosis and undergoing mitotic cell death, indicated by the fragmentation and hypercompaction of genomic material.
• Video 2 Time-lapse video microscopy of an ATRX-depleted HG-shATRX1 cell arrested in a prometaphase like state with no evidence of chromosome congression to the metaphase plate.
• Video 3 Time-lapse video microscopy of an ATRX-depleted HG-shATRX1 cell undergoing cycles of metaphase chromosome decondensation and recondensation.
• Video 4 Time-lapse video microscopy of an ATRX-depleted HG-shATRX1 cell prematurely initiating anaphase before completion of metaphase chromosome alignment.
| ||||||||||||||||||||||||||
|
|
