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Index of Online Supplemental Material for
J. Cell Biol. 10.1083/jcb.200708123
Sarmiento et al.
• Figure S1 WAVE1 KD has no affect on lamellipod formation.
• Figure S2 Quantitation of protein expression of siRNA KD cells.
• Figure S3 N-WASP and WAVE2 double KD has a more prominent tropomyosin compartment at the cell periphery and decreased Arp2/3 localization.
• Figure S4 KD of either mDia1 or 2 does not affect lamellipod protrusion at the leading edge.
• Figure S5 Cdc42 and Rac activity in N-WASP/WAVE2 KD cells.
• Video 1 Upon EGF stimulation, control MTLn3 cells exhibit lamellipod extension and accumulation of F-actin at the leading edge of the lamellipod.
• Video 2 N-WASP/WAVE2 siRNA KD cells exhibit jagged protrusions and increased filopod formation upon EGF stimulation.
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