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Index of Online Supplemental Material for
J. Cell Biol. 10.1083/jcb.200709033
Yamauchi et al.

Figure S1 Schwann cell migration requires the activation of the Rho family of small GTPases but is not dependent on Tiam1 or Dbs of the Dbl family GEFs.

Figure S2 Characterization of the anti-Dock7 and anti-(pTyr1118)Dock7 antibodies.

Figure S3 Purification of the DHR-2, wild-type, and Y1118F mutant proteins of Dock7.

Figure S4 The middle region 2 of Dock7 inhibits NRG1-induced migration and activation of Rac1 and Cdc42 in Cos-7 cells cotransfected with ErbB2 and ErbB3.

Figure S5 Dock7 does not interact with ELMO1 and CrkII.

Video 1 Vehicle-stimulated migration from reaggregates of control siRNA-transfected Schwann cells.

Video 2 Vehicle-stimulated migration from reaggregates of control siRNA-transfected Schwann cells.

Video 3 NRG1-stimulated migration from reaggregates of control siRNA-transfected Schwann cells.

Video 4 NRG1-stimulated migration from reaggregates of control siRNA-transfected Schwann cells.

Video 5 Vehicle-stimulated migration from reaggregates of Rac1 siRNA-transfected Schwann cells.

Video 6 NRG1-stimulated migration from reaggregates of Rac1 siRNA-transfected Schwann cells.

Video 7 Vehicle-stimulated migration from reaggregates of Cdc42 siRNA-transfected Schwann cells.

Video 8 NRG1-stimulated migration from reaggregates of Cdc42 siRNA-transfected Schwann cells.

Video 9 Vehicle-stimulated migration from reaggregates of Dock7 siRNA-transfected Schwann cells.

Video 10 NRG1-stimulated migration from reaggregates of Dock7 siRNA-transfected Schwann cells.

 





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