Home | Help | Feedback | Subscriptions | Archive | Search | Table of Contents

This Article Abstract Full Text Services Email this article Alert me to new content in the JCB Citing Articles Citing Articles via CrossRef

Index of Online Supplemental Material for
J. Cell Biol. 10.1083/jcb.200802005
Bird et al.

• Figure S1 Diagram of BAC modifications present in mTPX2^WT, mTPX2^AAA, and mTPX2^ΔN constructs.

• Figure S2 TPX2 RNAi reduces TPX2 protein expression to levels <5% of those of endogenous.

• Figure S3 Mouse TPX2 is efficiently expressed in cells after RNAi of human TPX2.

• Figure S4 TPX2 colocalizes with kinetochore fibers connecting lagging chromosomes.

• Figure S5 The TPX2–Aurora A interaction is required for calcium-stable microtubule stability and organization in prometaphase.

• Video 1 mTPX2-LAP rescues hTPX2(RNAi) and displays localization similar to that of hTPX2.

• Video 2 mTPX2^AAA is recruited to spindles and results in collapse of spindle poles and shorter spindle lengths.

• Video 3 mTPX2^ΔN is recruited to spindles and results in collapse of spindle poles and shorter spindle lengths.

• Video 4 α-Tubulin localization and spindle dynamics through mitosis in wild-type cells.

• Video 5 α-Tubulin localization and spindle dynamics through mitosis in cells depleted of TPX2.

• Video 6 α-Tubulin localization and spindle dynamics through mitosis in cells depleted of Aurora A.

 

This Article Abstract Full Text Services Email this article Alert me to new content in the JCB Citing Articles Citing Articles via CrossRef