December 5, 2016
The Rockefeller University Press
In the December 5th edition of biobytes, Taroh Kinoshita (Osaka University, Osaka, Japan) describes how GPI-anchored CRIPTO is released from the cell surface (Lee et al.), and Lisa Taneyhill (University of Maryland, College Park, MD) explains how the intracellular domain of Cadherin 6B promotes neural crest cell epithelial-to-mesenchymal transition (Schiffmacher et al.). Plus a round-up of other highlights from The Journal of Cell Biology. The show was written and produced by Caitlin Sedwick and Ben Short. Presented by Ben Short. See the associated papers in JCB for details on the funding provided to support these original research studies.
Timeline: 0:45 – CRIPTO shedding by PGAP6-mediated GPI processing; 8:00 – JCB round-up; 11:40 – Cad6B CTF2 regulates EMT effector genes