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Figure S4. Myr-TRAF4 induces PAK1-dependent cytoskeletal collapse. HUVECs cotransfected with actin-GFP and Myr-TRAF4 occasionally demonstrated actin skeleton collapse (left). Infection of cells with Ad-PAK1(K298A) (right) but not Ad-lacZ blocked actin collapse and increased stress fiber formation. Bar, 20 µm.