About the Cover
Cover picture: The position of nucleoporins (nups) in the yeast nuclear pore complex (NPC). A proteomic and biochemical analysis of the NPC revealed 29 different components exhibiting simple stoichiometries. Each of the components was tagged and its position determined by statistical analysis of the distribution of anti-tag, gold-labeled antibodies. A cross-section of the structure of the yeast NPC is shown in the background (kindly provided by Christopher Akey; Yang et al., 1998. Mol. Cell. 1:223-234). Shown (in green) are FG nups found on both sides of the NPC; FG nups found towards the periphery and exclusively on the nuclear side (blue) or the cytoplasmic side of the NPC (red); non-FG nups (gray); integral membrane proteins Pom34p (purple) and Pom152p and Ndc1p (purple stripes). See related article in this issue by Rout et al., 635-651.
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