In Focus:

Blood, stress, and tiRNAs

Ruth Williams Two studies identify the pathways to tRNA destruction under stress. J. Cell Biol. 2009 185: 3. Published Mar 30 2009, 10.1083/jcb.1851if. [Full Text] [PDF (536K)]  

People & Ideas:

Suzanne Pfeffer: Sorting through membrane trafficking

Caitlin Sedwick Pfeffer is writing the rulebook for membrane trafficking and protein sorting. J. Cell Biol. 2009 185: 4-5. Published Apr 6 2009, 10.1083/jcb.1851pi. [Full Text] [PDF (1042K)] [Metasepia pfefferi Movie]   

Feature:

Protease-dependent versus -independent cancer cell invasion programs: three-dimensional amoeboid movement revisited

Farideh Sabeh, Ryoko Shimizu-Hirota, and Stephen J. Weiss
J. Cell Biol. 2009 185: 11-19. Published Mar 30 2009, 10.1083/jcb.200807195. [Abstract] [Full Text] [PDF (2572K)]  

R e v i e w s   free access

Comments:

Transcription, chromatin condensation, and gene migration

James G. McNally
J. Cell Biol. 2009 185: 7-9. Published Apr 6 2009, 10.1083/jcb.200903056. [Abstract] [Full Text] [PDF (1147K)]  

Mini-Reviews:

Assembly of multiprotein complexes that control genome function

Christoffel Dinant, Martijn S. Luijsterburg, Thomas Höfer, Gesa von Bornstaedt, Wim Vermeulen, Adriaan B. Houtsmuller, and Roel van Driel
J. Cell Biol. 2009 185: 21-26. Published Mar 30 2009, 10.1083/jcb.200811080. [Abstract] [Full Text] [PDF (1272K)]  

R e s e a r c h    A r t i c l e s

Reports:

Exportin 4 mediates a novel nuclear import pathway for Sox family transcription factors

Cristina Gontan, Thomas Güttler, Erik Engelen, Jeroen Demmers, Maarten Fornerod, Frank G. Grosveld, Dick Tibboel, Dirk Görlich, Raymond A. Poot, and Robbert J. Rottier
J. Cell Biol. 2009 185: 27-34. Published Apr 6 2009, 10.1083/jcb.200810106. [Abstract] [Full Text] [PDF (3443K)] [PDF+supp data (5998K)] [Supplemental Material Index]   

Angiogenin cleaves tRNA and promotes stress-induced translational repression

Satoshi Yamasaki, Pavel Ivanov, Guo-fu Hu, and Paul Anderson
J. Cell Biol. 2009 185: 35-42. Published Mar 30 2009, 10.1083/jcb.200811106. [Abstract] [Full Text] [PDF (3742K)] [PDF+supp data (5351K)] [Supplemental Material Index] [Related biobytes podcast]   

The RNase Rny1p cleaves tRNAs and promotes cell death during oxidative stress in Saccharomyces cerevisiae

Debrah M. Thompson and Roy Parker
J. Cell Biol. 2009 185: 43-50. Published Mar 30 2009, 10.1083/jcb.200811119. [Abstract] [Full Text] [PDF (3110K)] [PDF+supp data (4657K)] [Supplemental Material Index] [Related biobytes podcast]   

A new model for binding of kinesin 13 to curved microtubule protofilaments

Anke M. Mulder, Alex Glavis-Bloom, Carolyn A. Moores, Michael Wagenbach, Bridget Carragher, Linda Wordeman, and Ronald A. Milligan
J. Cell Biol. 2009 185: 51-57. Published Mar 30 2009, 10.1083/jcb.200812052. [Abstract] [Full Text] [PDF (4470K)] [PDF+supp data (7355K)] [Supplemental Material Index]   

Strabismus regulates asymmetric cell divisions and cell fate determination in the mouse brain

Blue B. Lake and Sergei Y. Sokol
J. Cell Biol. 2009 185: 59-66. Published Mar 30 2009, 10.1083/jcb.200807073. [Abstract] [Full Text] [PDF (2441K)] [PDF+supp data (4000K)] [Supplemental Material Index] [Related biobytes podcast]   

Canonical Wnts function as potent regulators of osteogenesis by human mesenchymal stem cells

Guizhong Liu, Sapna Vijayakumar, Luca Grumolato, Randy Arroyave, HuiFang Qiao, Gal Akiri, and Stuart A. Aaronson
J. Cell Biol. 2009 185: 67-75. Published Apr 6 2009, 10.1083/jcb.200810137. [Abstract] [Full Text] [PDF (3518K)] [PDF+supp data (5324K)] [Supplemental Material Index]   

Molecular signatures of cell migration in C. elegans Q neuroblasts

Guangshuo Ou and Ronald D. Vale
J. Cell Biol. 2009 185: 77-85. Published Apr 6 2009, 10.1083/jcb.200812077. [Abstract] [Full Text] [PDF (5369K)] [PDF+supp data (9033K)] [Supplemental Material Index]   

Articles:

Large-scale chromatin structure of inducible genes: transcription on a condensed, linear template

Yan Hu, Igor Kireev, Matt Plutz, Nazanin Ashourian, and Andrew S. Belmont
J. Cell Biol. 2009 185: 87-100. Published Apr 6 2009, 10.1083/jcb.200809196. [Abstract] [Full Text] [PDF (3048K)] [PDF+supp data (3716K)] [Supplemental Material Index]   

hPOC5 is a centrin-binding protein required for assembly of full-length centrioles

Juliette Azimzadeh, Polla Hergert, Annie Delouvée, Ursula Euteneuer, Etienne Formstecher, Alexey Khodjakov, and Michel Bornens
J. Cell Biol. 2009 185: 101-114. Published Apr 6 2009, 10.1083/jcb.200808082. [Abstract] [Full Text] [PDF (7956K)] [PDF+supp data (10995K)] [Supplemental Material Index]   

miR-8 microRNAs regulate the response to osmotic stress in zebrafish embryos

Alex S. Flynt, Elizabeth J. Thatcher, Kristopher Burkewitz, Nan Li, Yinzi Liu, and James G. Patton
J. Cell Biol. 2009 185: 115-127. Published Mar 30 2009, 10.1083/jcb.200807026. [Abstract] [Full Text] [PDF (8752K)] [PDF+supp data (10120K)] [Supplemental Material Index]   

Rhabdomere biogenesis in Drosophila photoreceptors is acutely sensitive to phosphatidic acid levels

Padinjat Raghu, Elise Coessens, Maria Manifava, Plamen Georgiev, Trevor Pettitt, Eleanor Wood, Isaac Garcia-Murillas, Hanneke Okkenhaug, Deepti Trivedi, Qifeng Zhang, Azam Razzaq, Ola Zaid, Michael Wakelam, Cahir J O'Kane, and Nicholas Ktistakis
J. Cell Biol. 2009 185: 129-145. Published Apr 6 2009, 10.1083/jcb.200807027. [Abstract] [Full Text] [PDF (7928K)] [PDF+supp data (9710K)] [Supplemental Material Index]   

Integrin-linked kinase is required for radial sorting of axons and Schwann cell remyelination in the peripheral nervous system

Jorge A. Pereira, Yves Benninger, Reto Baumann, Ana Filipa Gonçalves, Murat Özçelik, Tina Thurnherr, Nicolas Tricaud, Dies Meijer, Reinhard Fässler, Ueli Suter, and João B. Relvas
J. Cell Biol. 2009 185: 147-161. Published Apr 6 2009, 10.1083/jcb.200809008. [Abstract] [Full Text] [PDF (4478K)] [PDF+supp data (8331K)] [Supplemental Material Index]   

The Na⁺/H⁺ exchanger NHE1 is required for directional migration stimulated via PDGFR- in the primary cilium

Linda Schneider, Christian-Martin Stock, Peter Dieterich, Bo Hammer Jensen, Lotte Bang Pedersen, Peter Satir, Albrecht Schwab, Søren Tvorup Christensen, and Stine Falsig Pedersen
J. Cell Biol. 2009 185: 163-176. Published Apr 6 2009, 10.1083/jcb.200806019. [Abstract] [Full Text] [PDF (4718K)] [PDF+supp data (6223K)] [ Supplemental Material Index]   

O f    I n t e r e s t

From J. Exp. Med.:

The Wiskott-Aldrich syndrome protein is required for iNKT cell maturation and function

Michela Locci, Elena Draghici, Francesco Marangoni, Marita Bosticardo, Marco Catucci, Alessandro Aiuti, Caterina Cancrini, Laszlo Marodi, Teresa Espanol, Robbert G.M. Bredius, Adrian J. Thrasher, Ansgar Schulz, Jiri Litzman, Maria Grazia Roncarolo, Giulia Casorati, Paolo Dellabona, and Anna Villa [Full Text]  

Transcriptional complexes formed by NFAT dimers regulate the induction of T cell tolerance

Noemi Soto-Nieves, Irene Puga, Brian T. Abe, Sanmay Bandyopadhyay, Ian Baine, Anjana Rao, and Fernando Macian [Full Text]  

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