To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.
[Index by Author] 

P o d c a s t s   free access

September 21, 2009 The regular packing of lens fiber cells is maintained by Tropomodulin 1 and the spectrin-actin network; IL-9 promiscuity and T helper cell plasticity; TOR-mediated autophagy regulates cell death in Drosophila neurodegenerative disease

N e w s   free access

In This Issue:

In Focus:

Rab2 directs a stop-loss program

Ben Short Small GTPase supports dense core vesicle maturation in worm neurons. J. Cell Biol. 2009 186: 769. Published Sep 21 2009, 10.1083/jcb.1866if. [Full Text] [PDF (548K)]  

People & Ideas:

Iain Cheeseman: A strong attachment to kinetochores

Ben Short Cheeseman is looking forward to a new era of research on chromosome segregation. J. Cell Biol. 2009 186: 770-771. Published Sep 14 2009, 10.1083/jcb.1866pi. [Full Text] [PDF (561K)]  

R e v i e w s   free access

Review:

Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes

Anne Simonsen and Sharon A. Tooze
J. Cell Biol. 2009 186: 773-782. Published Sep 21 2009, 10.1083/jcb.200907014. [Abstract] [Full Text] [PDF (2373K)]  

R e s e a r c h    A r t i c l e s

Reports:

Role of ERO1-–mediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress–induced apoptosis

Gang Li, Marco Mongillo, King-Tung Chin, Heather Harding, David Ron, Andrew R. Marks, and Ira Tabas CHOP turns on ERO1- to release calcium via IP3R and trigger cell death in response to ER stress. J. Cell Biol. 2009 186: 783-792. Published Sep 14 2009, 10.1083/jcb.200904060. [Abstract] [Full Text] [PDF (6269K)] [PDF+supp data (7262K)] [Supplemental Material]   

Coassembly of Mgm1 isoforms requires cardiolipin and mediates mitochondrial inner membrane fusion

Rachel M. DeVay, Lenin Dominguez-Ramirez, Laura L. Lackner, Suzanne Hoppins, Henning Stahlberg, and Jodi Nunnari The soluble and membrane-anchored isoforms of Mgm1 are only active when they work together (in trans). J. Cell Biol. 2009 186: 793-803. Published Sep 14 2009, 10.1083/jcb.200906098. [Abstract] [Full Text] [PDF (5252K)]  

The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice

Junko Wakabayashi, Zhongyan Zhang, Nobunao Wakabayashi, Yasushi Tamura, Masahiro Fukaya, Thomas W. Kensler, Miho Iijima, and Hiromi Sesaki Brain-specific Drp1 knockout mice demonstrate that Drp1-mediated organelle division is important for development, mitochondrial morphogenesis, and apoptosis. J. Cell Biol. 2009 186: 805-816. Published Sep 14 2009, 10.1083/jcb.200903065. [Abstract] [Full Text] [PDF (9056K)] [PDF+supp data (12110K)] [ Supplemental Material]   

Regulation of dynein-driven microtubule sliding by the axonemal protein kinase CK1 in Chlamydomonas flagella

Avanti Gokhale, Maureen Wirschell, and Winfield S. Sale CK1 puts the brakes on dynein activity when added to purified axonemes in vitro, presumably to regulate how flagella bend. J. Cell Biol. 2009 186: 817-824. Published Sep 14 2009, 10.1083/jcb.200906168. [Abstract] [Full Text] [PDF (2456K)] [PDF+supp data (3383K)] [Supplemental Material]   

Articles:

Entropic organization of interphase chromosomes

Peter R. Cook and Davide Marenduzzo Nonspecific forces, in addition to biophysical properties, lead to the careful arrangement of chromosomes in the nucleus. J. Cell Biol. 2009 186: 825-834. Published Sep 14 2009, 10.1083/jcb.200903083. [Abstract] [Full Text] [PDF (1924K)]  

Nucleotide excision repair–induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response

Jurgen A. Marteijn, Simon Bekker-Jensen, Niels Mailand, Hannes Lans, Petra Schwertman, Audrey M. Gourdin, Nico P. Dantuma, Jiri Lukas, and Wim Vermeulen The epigenetic mark indicative of DNA UV damage or double-strand breaks is achieved via a common pathway regardless of the cause of damage. J. Cell Biol. 2009 186: 835-847. Published Sep 21 2009, 10.1083/jcb.200902150. [Abstract] [Full Text] [PDF (6841K)] [PDF+supp data (12525K)] [Supplemental Material]   

Ribosome stalk assembly requires the dual-specificity phosphatase Yvh1 for the exchange of Mrt4 with P0

Kai-Yin Lo, Zhihua Li, Feng Wang, Edward M. Marcotte, and Arlen W. Johnson The step by step assembly process from preribosome in the nucleus to translation-competent 60S ribosome subunit in the cytoplasm is revealed (also see Kemmler et al. in this issue). J. Cell Biol. 2009 186: 849-862. Published Sep 21 2009, 10.1083/jcb.200904110. [Abstract] [Full Text] [PDF (3102K)] [PDF+supp data (4453K)] [Supplemental Material]   

Yvh1 is required for a late maturation step in the 60S biogenesis pathway

Stefan Kemmler, Laura Occhipinti, Maria Veisu, and Vikram Govind Panse The step by step assembly process from preribosome in the nucleus to translation-competent 60S ribosome subunit in the cytoplasm is revealed (also see Lo et al. in this issue). J. Cell Biol. 2009 186: 863-880. Published Sep 21 2009, 10.1083/jcb.200904111. [Abstract] [Full Text] [PDF (4282K)] [PDF+supp data (4343K)] [Supplemental Material]   

Impaired dense core vesicle maturation in Caenorhabditis elegans mutants lacking Rab2

Stacey L. Edwards, Nicole K. Charlie, Janet E. Richmond, Jan Hegermann, Stefan Eimer, and Kenneth G. Miller Uncoordinated movement in Rab2 mutants is caused by impaired retention of cargo on dense core vesicles, not by defective synaptic vesicle release. (Also see the companion article by Sumakovic et al. in this issue.) J. Cell Biol. 2009 186: 881-895. Published Sep 21 2009, 10.1083/jcb.200902095. [Abstract] [Full Text] [PDF (5086K)] [PDF+supp data (7909K)] [Supplemental Material]   

UNC-108/RAB-2 and its effector RIC-19 are involved in dense core vesicle maturation in Caenorhabditis elegans

Marija Sumakovic, Jan Hegermann, Ling Luo, Steven J. Husson, Katrin Schwarze, Christian Olendrowitz, Liliane Schoofs, Janet Richmond, and Stefan Eimer Uncoordinated movement in Rab2 mutants is caused by impaired retention of cargo on dense core vesicles, not by defective synaptic vesicle release. (Also see the companion article by Edwards et al. in this issue.) J. Cell Biol. 2009 186: 897-914. Published Sep 21 2009, 10.1083/jcb.200902096. [Abstract] [Full Text] [PDF (10741K)] [PDF+supp data (14353K)] [Supplemental Material]   

Tropomodulin1 is required for membrane skeleton organization and hexagonal geometry of fiber cells in the mouse lens

Roberta B. Nowak, Robert S. Fischer, Rebecca K. Zoltoski, Jerome R. Kuszak, and Velia M. Fowler The spectrin–actin network is disrupted in Tmod1 mutants, disturbing fiber cell morphology, and disordering lens cell organization. J. Cell Biol. 2009 186: 915-928. Published Sep 14 2009, 10.1083/jcb.200905065. [Abstract] [Full Text] [PDF (10962K)] [PDF+supp data (14492K)] [Supplemental Material] [Related biobytes podcast]   

Corrections:

Recruitment of functionally distinct membrane proteins to chromatin mediates nuclear envelope formation in vivo

Daniel J. Anderson, Jesse D. Vargas, Joshua P. Hsiao, and Martin W. Hetzer J. Cell Biol. 2009 186: 929. Published Sep 21 2009, 10.1083/jcb.20090110620090903c. [Full Text] [PDF (1079K)]  

O f    I n t e r e s t

From J. Exp. Med.:

Loss of SOCS3 expression in T cells reveals a regulatory role for interleukin-17 in atherosclerosis

Soraya Taleb, Mélissa Romain, Bhama Ramkhelawon, Catherine Uyttenhove, Gerard Pasterkamp, Olivier Herbin, Bruno Esposito, Nicolas Perez, Hideo Yasukawa, Jacques Van Snick, Akihiko Yoshimura, Alain Tedgui, and Ziad Mallat [Full Text]  

The angiopietin-1–Tie2 pathway prevents rather than promotes pulmonary arterial hypertension in transgenic mice

Lakshmi Kugathasan, Julie Basu Ray, Yupu Deng, Effat Rezaei, Daniel J. Dumont, and Duncan J. Stewart [Full Text]  

XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development

Derrick J. Todd, Louise J. McHeyzer-Williams, Czeslawa Kowal, Ann-Hwee Lee, Bruce T. Volpe, Betty Diamond, Michael G. McHeyzer-Williams, and Laurie H. Glimcher [Full Text]  

From J. Gen. Physiol.:

EF hands at the N-lobe of calmodulin are required for both SK channel gating and stable SK–calmodulin interaction

Weiyan Li, David B. Halling, Amelia W. Hall, and Richard W. Aldrich [Full Text]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.