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[Index by Author] 

P o d c a s t s   free access

October 19, 2009 RIDα rescues NPC sorting defects; Division-independent egress of stem cells; Interaction between Cripto-1 and Notch receptors

N e w s   free access

In This Issue:

In Focus:

Adhering to the message

Ben Short How cell adhesion molecules transmit signals across the plasma membrane. J. Cell Biol. 2009 187: 445. Published Nov 16 2009, 10.1083/jcb.1874if. [Full Text] [PDF (525K)]  

People & Ideas:

Michael Buszczak: Tracking the big game in stem cell identity

Caitlin Sedwick Buszczak is exploring the regulation of proteins that control stem cell identity in the fly. J. Cell Biol. 2009 187: 446-447. Published Nov 16 2009, 10.1083/jcb.1874pi. [Full Text] [PDF (717K)]  

R e v i e w s   free access

Meeting Review:

Journeys through the Golgi—taking stock in a new era

Scott Emr, Benjamin S. Glick, Adam D. Linstedt, Jennifer Lippincott-Schwartz, Alberto Luini, Vivek Malhotra, Brad J. Marsh, Akihiko Nakano, Suzanne R. Pfeffer, Catherine Rabouille, James E. Rothman, Graham Warren, and Felix T. Wieland
J. Cell Biol. 2009 187: 449-453. Published Nov 9 2009, 10.1083/jcb.200909011. [Abstract] [Full Text] [PDF (1912K)]  

R e s e a r c h    A r t i c l e s

Reports:

Cohesinopathy mutations disrupt the subnuclear organization of chromatin

Scarlett Gard, William Light, Bo Xiong, Tania Bose, Adrian J. McNairn, Bethany Harris, Brian Fleharty, Chris Seidel, Jason H. Brickner, and Jennifer L. Gerton Nuclear morphology, chromosomal condensation, and transcriptional-mediated localization of genes to the nuclear periphery are disturbed by mutations in cohesin pathway genes. J. Cell Biol. 2009 187: 455-462. Published Nov 9 2009, 10.1083/jcb.200906075. [Abstract] [Full Text] [PDF (4174K)] [PDF+supp data (5146K)] [Supplemental Material]   

A dual function for Pex3p in peroxisome formation and inheritance

Joanne M. Munck, Alison M. Motley, James M. Nuttall, and Ewald H. Hettema Pex3p interacts with peroxisome retention factor Inp1p at the peroxisomal membrane and functions in the organelle’s segregation in addition to its biogenesis. J. Cell Biol. 2009 187: 463-471. Published Nov 9 2009, 10.1083/jcb.200906161. [Abstract] [Full Text] [PDF (3964K)] [PDF+supp data (4781K)] [Supplemental Material]   

Drosophila glypicans regulate the germline stem cell niche

Yoshiki Hayashi, Satoru Kobayashi, and Hiroshi Nakato Heparan sulfate glycoproteins dally and dally-like define the germ cell niche in female and male Drosophila, respectively. J. Cell Biol. 2009 187: 473-480. Published Nov 9 2009, 10.1083/jcb.200904118. [Abstract] [Full Text] [PDF (3376K)] [PDF+supp data (4625K)] [Supplemental Material]   

Articles:

Quantitative analysis of chromatin compaction in living cells using FLIM–FRET

David Llères, John James, Sam Swift, David G. Norman, and Angus I. Lamond FRET analysis of cell lines expressing fluorescently tagged histones on separate nucleosomes demonstrates that variations in chromosome compaction occur during mitosis. J. Cell Biol. 2009 187: 481-496. Published Nov 16 2009, 10.1083/jcb.200907029. [Abstract] [Full Text] [PDF (4069K)] [PDF+supp data (6297K)] [Supplemental Material]   

Lte1 contributes to Bfa1 localization rather than stimulating nucleotide exchange by Tem1

Marco Geymonat, Adonis Spanos, Geoffroy de Bettignies, and Steven G. Sedgwick Reevaluation of Lte1’s involvement in the mitotic exit network reveals that it is involved in localizing Bfa1 to the spindle pole body but does not function as a GEF for Tem1. J. Cell Biol. 2009 187: 497-511. Published Nov 16 2009, 10.1083/jcb.200905114. [Abstract] [Full Text] [PDF (2996K)] [PDF+supp data (3558K)] [Supplemental Material]   

Capacity for stochastic self-renewal and differentiation in mammalian spermatogonial stem cells

Zhuoru Wu, Katherine Luby-Phelps, Abhijit Bugde, Laura A. Molyneux, Bray Denard, Wen-Hong Li, Gürol M. Süel, and David L. Garbers Spermatogonial stem cells have an innate ability to choose, with constant probability, between different fates independently of cues from the microenvironment. J. Cell Biol. 2009 187: 513-524. Published Nov 9 2009, 10.1083/jcb.200907047. [Abstract] [Full Text] [PDF (6025K)] [PDF+supp data (7165K)] [Supplemental Material]   

Membrane expansion alleviates endoplasmic reticulum stress independently of the unfolded protein response

Sebastian Schuck, William A. Prinz, Kurt S. Thorn, Christiane Voss, and Peter Walter Increasing the size of the ER by lipid synthesis helps the cell deal with ER stress. J. Cell Biol. 2009 187: 525-536. Published Nov 9 2009, 10.1083/jcb.200907074. [Abstract] [Full Text] [PDF (4371K)] [PDF+supp data (5868K)] [Supplemental Material]   

Adenovirus RID- activates an autonomous cholesterol regulatory mechanism that rescues defects linked to Niemann-Pick disease type C

Nicholas L. Cianciola and Cathleen R. Carlin Viral subversion of cholesterol homeostasis provides insights into sterol trafficking, autophagy, and lysosomal storage diseases. J. Cell Biol. 2009 187: 537-552. Published Nov 16 2009, 10.1083/jcb.200903039. [Abstract] [Full Text] [PDF (9704K)] [PDF+supp data (10496K)] [ Supplemental Material] [Related biobytes podcast]   

The CEACAM1 N-terminal Ig domain mediates cis- and trans-binding and is essential for allosteric rearrangements of CEACAM1 microclusters

Esther Klaile, Olga Vorontsova, Kristmundur Sigmundsson, Mario M. Müller, Bernhard B. Singer, Lars-Göran Öfverstedt, Stina Svensson, Ulf Skoglund, and Björn Öbrink Structural analyses reveal that oligomerization between cell adhesion molecules in the same membrane is influenced by their interactions across opposing membranes (see also in this issue the accompanying paper by Müller et al.). J. Cell Biol. 2009 187: 553-567. Published Nov 16 2009, 10.1083/jcb.200904149. [Abstract] [Full Text] [PDF (3704K)] [PDF+supp data (4457K)] [Supplemental Material]   

Homophilic adhesion and CEACAM1-S regulate dimerization of CEACAM1-L and recruitment of SHP-2 and c-Src

Mario M. Müller, Esther Klaile, Olga Vorontsova, Bernhard B. Singer, and Björn Öbrink The monomer/dimer equilibrium of adhesion molecule CEACAM1-L is regulated by binding between opposing membranes, which in turn controls cytoplasmic enzyme binding and signaling (see also in this issue the accompanying paper by Klaile et al.). J. Cell Biol. 2009 187: 569-581. Published Nov 16 2009, 10.1083/jcb.200904150. [Abstract] [Full Text] [PDF (5613K)] [PDF+supp data (8124K)] [Supplemental Material]   

O f    I n t e r e s t

From J. Exp. Med.:

Niche recycling through division-independent egress of hematopoietic stem cells

Deepta Bhattacharya, Agnieszka Czechowicz, A.G. Lisa Ooi, Derrick J. Rossi, David Bryder, and Irving L. Weissman [Full Text]  

Transcellular migration of leukocytes is mediated by the endothelial lateral border recycling compartment

Zahra Mamdouh, Alexei Mikhailov, and William A. Muller [Full Text]  

Histone H2AX stabilizes broken DNA strands to suppress chromosome breaks and translocations during V(D)J recombination

Bu Yin, Velibor Savic, Marisa M. Juntilla, Andrea L. Bredemeyer, Katherine S. Yang-Iott, Beth A. Helmink, Gary A. Koretzky, Barry P. Sleckman, and Craig H. Bassing [Full Text]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.