PT  - JOURNAL ARTICLE
AU  - Gordon, Leslie B.
AU  - Cao, Kan
AU  - Collins, Francis S.
TI  - Progeria: Translational insights from cell biology
AID  - 10.1083/jcb.201207072
DP  - 2012 Oct 01
TA  - The Journal of Cell Biology
PG  - 9--13
VI  - 199
IP  - 1
4099  - http://jcb.rupress.org/content/199/1/9.short
4100  - http://jcb.rupress.org/content/199/1/9.full
SO  - J Cell Biol2012 Oct 01; 199
AB  - Cell biologists love to think outside the box, pursuing many surprising twists and unexpected turns in their quest to unravel the mysteries of how cells work. But can cell biologists think outside the bench? We are certain that they can, and clearly some already do. To encourage more cell biologists to venture into the realm of translational research on a regular basis, we would like to share a handful of the many lessons that we have learned in our effort to develop experimental treatments for Hutchinson-Gilford progeria syndrome (HGPS), an endeavor that many view as a “poster child” for how basic cell biology can be translated to the clinic.