Table II.

Increasing aneuploidy in lymphocytes from Bub1 transgenic mice

Mouse genotypeAge (n)Mitotic figures inspectedAneuploid figures (SD)Karyotypes with indicated chromosome numberMitotic figures with PMSCS (SD)
3637383940414243
%%
WT1 d (3)1501 (1)114811 (1)
WT6 wk (3)1502 (2)214711 (2)
WT5 mo (3)1504 (0)1214431 (1)
Bub1T851 d (3)15021 (3)33514119513 (1)
Bub1T856 wk (3)15031 (2)181710413433 (1)
Bub1T855 mo (3)15035 (6)44112397831 (2)
Bub1T2641 d (3)15015 (2)2148127710 (0)
Bub1T2646 wk (3)15030 (3)416151051453 (1)
Bub1T2645 mo (3)15028 (2)218161081236 (3)
  • Empty spaces mean that there were no karyotypes with the indicated chromosome number.