Table II

Quantification of Blood Vessels in Tissue Sections

TissueBlood vessels per 40× field*
Thbs2 +/+Thbs2 −/−
Adult adipose 7.4 ± 1.2‡17.3 ± 2.3
Embryonic adipose 9.7 ± 3.117.2 ± 5.6
Adult dermis 5.1 ± 2.010.0 ± 2.4
Neonatal dermis 8.9 ± 2.812.9 ± 2.8
Embryonic dermis18.8 ± 2.222.5 ± 3.5
Embryonic thymus13.1 ± 1.522.9 ± 2.4
  • *  Sections were imunostained with an antibody to vWF. Counts are the averages of 7–20 40× microscopic fields (0.075 mm2/field) obtained by examination of 6 μm sections from four control and three mutant mice.  

  •  Standard deviation. All differences between sections from TSP2 +/+ and TSP2 −/− mice are significant at a level of P ⩽ 0.001, with the exception of embryonic dermis for which the level of significance is P ⩽ 0.04.