Table III

Effect of Single and Double Mutations at Thr 7, Ser 13, and Ser 38 on Formation of GFAP Bridge-like Structures

MutantsRelative scores of bridge-like structure
%
m(7,13,38)100
Wild type 0 ± 0
m(7) 1.3 ± 0.49
m(13)4.8 ± 3.4
m(38)   26 ± 1.6
m(7,13)8.7 ± 1.8
m(7,38) 43 ± 12
m(13,38) 81 ± 2.5
  • Population of cells with GFAP bridge-like structures relative to that of m(7, 13, 38) was scored. The results are expressed as the mean ± SD of three independent experiments. In each experiment, at least 2,000 cells were counted.