Table 1

Effect of Krox20-cre–induced Mutation of erbB2 on Schwann Cell Number

SciaticVentral rootDorsal root
MutantControlMutantControlMutantControl
P3.5564 ± 31588 ± 275 ± 251 ± 36 ± 233 ± 4
P15395 ± 12409 ± 2118 ± 374 ± 496 ± 10179 ± 5
P 6 mo209 ± 33204 ± 2040 ± 1341 ± 7101 ± 9112 ± 8
  • Schwann cell nuclei were counted from semi-thin sections of nerves at the indicated ages; values are displayed as numbers of nuclei per section. The number of nuclei within spinal roots at P3.5 was determined from sections of lumbar blocks (L4-L5 level); at later stages, L5 roots were examined. Data are shown as mean ± SD.