Table 5

Effect of tau and map1b Mutation on Neuronal Differentiation in Cultured Hippocampal Neurons

Percentage of neurons at stage 3n
tau+/+map1b+/+88.7 ± 2.46
tau−/−map1b+/+86.3 ± 2.74
tau+/+map1b−/−80.4 ± 2.44
tau−/−map1b−/−73.4 ± 2.15
  • Percentage of cells at stage 3 (stage of axonal elongation). Cells stained with a monoclonal antibody against tubulin were examined. n, number of animals examined. A total of 100–160 cells per animal were analyzed. The means ± SEM are shown.