Table 1

Dissociation Constants for Nucleoporins and Importin β in the Presence or Absence of the IBB Domain

Kd apparent
Recombinant nucleoporinImportin βImportin β + IBB domain
nMnM
Nup 358-1 (996–1963)216 ± 16.6 (3)210 ± 15 (3)
Nup 358-4 (2500–3224)225 ± 14.4 (4)220 ± 16 (3)
Nup 62100 ± 8 (6)105 ± 6 (6)
Nup 58101 ± 2 (5)106.7 ± 8 (5)
Nup 54111.5 ± 6.5 (4)108.5 ± 8.5 (4)
Nup 153-C (609–1475)9 ± 2.5 (6)9.4 ± 3 (5)