Table II.

CXCR1 and CXCR2 internalization in the presence of various stimuli

IL-8 receptorIL-8 alonefMLP aloneIL-8 + fMLPIL-8 + fMLP + SB203580
%
CXCR178.3 ± 1.714.9 ± 13.882.8 ± 5.790.8 ± 1.5
CXCR272.0 ± 9.612.5 ± 4.874.3 ± 1.269.6 ± 1.7
  • Results are shown as the percentage of internalization ± SEM. n = 2 for IL-8 + fMLP and IL-8 + fMLP + SB203580. n = 3 for IL-8 and fMLP.