Table I.

PP1-interacting proteins identified by combined SILAC/proteomics

Accession numberProtein nameIsoform preferenceMolecular massNumber of unique
 peptides quantifiedCanonical RVXF
 motifReferences
kD
Known PP1 binding
 proteins
    P49750ZAP3None219.950+Tran et al., 2004
    Q75MG7KPI-2PP1γ164.92+Wang and Brautigan, 2002
    Q13625p53bp2PP1α125.613+Helps et al., 1995
    Q96QC0P99/PNUTSPP1α99.19+Kreiviet al., 1997; Allen et al., 1998
    Q96SB3Neurabin II/
     SpinophilinNone89.521+Hsieh-Wilson et al., 1999
    Q12972NIPP1PP1α38.58+Van Eynde et al., 1995;
     Trinkle-Mulcahy et al., 1999
Novel PP1-
 interacting proteins
    Q9H9B9RIF1, isoform 4PP1α274.69+
    Q5VV35MyopalladinPP1α145.33+
    Q69YH5Repo-ManPP1γ112.74+
    Q01844EWSPP1α68.53+
    Q68CK8KIAA1949PP1α67.94+
    O94842LCP1PP1γ66.21
    Q8NCH2FLJ90254PP1α47.34+
    Q6ZUJ6FLJ43651PP1α42.88
    Q6UXN9WD40None35.25