Table I.

Quantification of mRNA and protein levels of m-mag in different transgenic lines, and induction by withdrawal of doxycycline

LineDoxNBWBIHC
L16563 ± 1270 ± 8
L24057 ± 1468 ± 3
L3100100 ± 7100 ± 4
L413 ± 15 ± 2
L3Dox101 ± 1
L3wd 3d7292 ± 656 ± 7
L3wd 6d10296 ± 997 ± 6
  • Quantification of Northern blot analysis (NB), immunohistochemistry (IHC), and Western blot analysis (WB). Values show expression levels of m-mag in skeletal muscles of mouse lines L1–L4. Data of line L3 after suppression of expression by doxycycline (Dox) and subsequent withdrawal for 3 (wd 3d) or 6 d (wd 6d) are relative to levels measured in mouse line L3. Values represent the mean ± the SEM. n ≥ 3.