Table II.

Quantification of laminin-α5 and α-dystroglycan detected at the membrane of triceps brachii

StrainLaminin-α5α-Dystroglycan
WT100 ± 17100 ± 13
dyW/dyW138 ± 927 ± 6
dyW/c-mag373 ± 3371 ± 14
dyW/m-mag 3d365 ± 1764 ± 18
dyW/m-mag 14d409 ± 1761 ± 10
dyW/m-mag 28d368 ± 1663 ± 17
  • Expression levels of laminin-α5 and α-dystroglycan were comparable in dyW/c-mag and dyW/m-mag mice starting expression in advanced stages of the disease. Values are relative to WT mice and represent the mean ± the SEM. n ≥ 3.