Table I.

Relative fold change of protein expression in OTCs with FPPARβ/δ compared with FCTRL

Cytokines/growth factorsFold increasea
KGFb4.01 ± 0.11c
IL-6b5.56 ± 0.02c
IL-8b2.94 ± 0.14d
IL-102.13 ± 0.07c
IL-162.86 ± 0.11d
GMCSFb5.26 ± 0.10c
I-3093.33 ± 0.16c
Eotaxin-23.03 ± 0.12c
VEGF0.25 ± 0.011d
PIGF0.33 ± 0.014d
  • a The intensities of signals were quantified by densitometry. Positive control included in the array blot was used to normalize and compare the results from different membranes. Values obtained from the control KCTRL/FCTRL OTC were arbitrarily assigned a value of 1. Values represent the mean fold increase as compared with control OTC (n = 3).

  • b mRNA expression levels of these genes were further verified by qPCR.

  • c P < 0.01.

  • d P < 0.1.