Table I.

Density of filopodia, thin spines, mushroom spines, and stubby spines

Descriptionn (neurons); DIVFilopodia (mean ± SEM)Thin spines (mean ± SEM)Mushroom spines (mean ± SEM)Stubby spines (mean ± SEM)
µm−1µm−1µm−1µm−1
GFP control16; 120.18 ± 0.0160.11 ± 0.0140.038 ± 0.0100.0096 ± 0.0031
Cdc42 GDP15; 120.21 ± 0.0280.017 ± 0.00420.013 ± 0.00440.018 ± 0.0059
Cdc42 GTP17; 120.12 ± 0.0160.024 ± 0.00600.039 ± 0.00730.054 ± 0.011
GFP control16; 120.13 ± 0.0160.090 ± 0.0110.029 ± 0.00490.0097 ± 0.0026
Inactive Rif18; 120.089 ± 0.00780.034 ± 0.00400.049 ± 0.00940.049 ± 0.0070
p34 siRNA12; 120.14 ± 0.0200.015 ± 0.00380.018 ± 0.00780.0065 ± 0.0017
cof1 siRNA16; 120.12 ± 0.0130.043 ± 0.00470.025 ± 0.00440.0060 ± 0.0016
cof1 siRNA + cof1-myc14; 120.14 ± 0.0170.12 ± 0.0160.024 ± 0.00300.011 ± 0.0077
GFP control14; 120.17 ± 0.0160.091 ± 0.0130.035 ± 0.00760.0058 ± 0.0019
Active Rif18; 120.16 ± 0.0160.058 ± 0.0100.023 ± 0.00470.0056 ± 0.0010
GFP control19; 12–130.16 ± 0.0160.11 ± 0.0110.030 ± 0.00510.0078 ± 0.0020
mDia2 siRNA12; 12–130.11 ± 0.0220.056 ± 0.0130.031 ± 0.00460.017 ± 0.0040
GFP control12; 12, and 140.17 ± 0.0120.16 ± 0.0220.027 ± 0.00560.015 ± 0.0045
Inactive Rif + active mDia212; 12, and 140.23 ± 0.0320.011 ± 0.00700.012 ± 0.00590.015 ± 0.0091
GFP control13; 120.18 ± 0.0150.11 ± 0.0140.037 ± 0.00570.0081 ± 0.0018
Inactive Rif + WA18; 120.21 ± 0.0210.019 ± 0.00580.0027 ± 0.00150.0030 ± 0.0017
W14; 120.12 ± 0.0160.093 ± 0.0150.036 ± 0.00640.021 ± 0.0027
WA15; 120.11 ± 0.0150.011 ± 0.00250.0093 ± 0.00280.0068 ± 0.0019